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If you are planning to use Picamilon supplements to enhance your cognitive function, productivity and mood, reading user reviews and experiences with this nootropic is an excellent starting point.
Much of the best information about how this energy-boosting biosynthetic compound works comes from testimonials posted by users online. There are so many different nootropic available for reducing and anxiety and helping you focus that it can be difficult to decide which one to use.
One thing pointed out by many Picamilon reviews is that this brain supplement makes you feel relaxed but also has a mildly stimulating effect. This makes the Picamilon experience unique from other anxiolytic nootropics that are more sedative-like in their nature.
In this Picamilon review, we will give you a better understanding of what this nootropic is, its neurological effects and the typical experience you can expect when using it.
Mood
Anxiety
Sleep- Consists of GABA & Niacin
- Stimulates GABA receptors in the brain
- Promotes mood, sleep & relaxation
What Is Picamilon?
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Picamilon is a potent Nootropic supplement that was developed in the Soviet Union during the Cold War.
Although it has actually been in continuous use throughout Europe since that time, it has only recently caught the attention of Western medicine.
This supplement is a combination of the natural mineral Niacin and the powerful neurotransmitter GABA.
Many anti-anxiety, anti-stress and anti-depression supplements work on the GABA systems in your brain because this is the chief neurotransmitter connected to sensations of peace and contentment. GABA works essentially to calm the mind down when it is hyperactive and high-strung by moderating the firing rate of your neurons.
Niacin is an essential nutrient normally associated with the digestion of carbohydrates and the healthy functioning of skin and eyes. It is also heavily involved in maintaining the proper working of the nervous system.
You will find it in small doses in energy drinks like Red Bull because it improves the energy level in your brain, resulting in greater clarity of mind and higher levels of motivation.
How Picamilon Works:
We can think of Picamilon as essentially a delivery system for GABA and Niacin to the brain. GABA itself cannot cross into the brain when you take it in an oral supplement form. However, Picamilon can reach the brain tissue because of the presence of niacin in the chemical structure of this molecule.
As Picamilon is absorbed into the bloodstream through the intestinal tract, it crosses over the blood-brain barrier and reaches the central nervous system. The compound is then separated into its two constituent elements through a process called hydrolysis. This leads to higher GABA levels as well as higher Niacin levels being present in the brain.
The GABA then attaches itself to various receptor sites and provokes an anti-anxiety response. While the Niacin is primarily active as a transporter to carry the GABA into the central nervous system it does have a number of workings on its own.
For example, it actually opens up blood passageways within the brain. This process is known as vasodilation and it makes it possible to have an increased level of blood flow and circulation within the brain. When you have more blood circulating to the brain, you also have more nutrients being delivered and more toxins being removed.
As such, Niacin increases oxygen and glucose availability to the brain and can help to detox your brain cells.
Picamilon Review:
The benefits associated with Picamilon range from Nootropic in nature to more health related areas. Improved cerebral blood flow and circulation may explain the enhanced mental focus and clarity that many users experience.
Some individuals have even seen success in using it to treat mild cases of Attention Deficit Disorder.
In addition to these mental effects, the supplement has been shown to be effective at restoring the brain to normal function after acute alcohol intoxication and a number of other issues. It can be useful for improving visual function in glaucoma patients.
Most people use Picamilon for its effects upon the mood. This is primarily due to the increase in GABA levels. As this goes to work the brain neurons are inhibited from their continued firing, forcing a shutdown of excess brain activity.
From a medical standpoint, anxiety and nervousness are associated with over-excitement of certain areas of your brain. Picamilon supplements can reduce this harmful activity which leads to a reduction of stress levels, anxiety and possibly even depression.
Many people find themselves better able to relax and fall asleep while using this supplement. Once asleep, the experience will usually be more restful and peaceful with higher levels of REM sleep and dreaming.
Picamilon is also capable of reducing blood pressure in the rest of your body. GABA stimulation has some effect on this by lowering some of the natural stress responses in the brain that can contribute to higher blood pressure.
Niacin also goes about opening up the blood vessels and passageways in the brain, helping to improve cerebral blood flow and circulation, lessening the pressure on the existing blood vessels.
Typical User Picamilon Experiences:
One of the more interesting experiences that many users have had with Picamilon is that of helping to alleviate the side effects of stimulants.
Specifically, it is used in nootropic stacks by users looking to block or avoid the anxiety and agitation that often results from using stimulants. For anyone taking smart drugs like Modafinil, Adrafinil, Armodafinil, Adderall, Ritalin or even Caffeine this can be highly beneficial, preventing some of the associated tension and restlessness that can occur.
Picamilon is not only effective at this, but it also does not interfere in the ‘good’ stimulant-like effects and can contribute to better concentration and energy.
The most common experience or result that users have when taking Picamilon is that of achieving a balanced and focused state of composure. Picamilon reviews usually say that this is an excellent nootropic for enhancing your productivity without leaving you burned out or stressed out.
The relaxation effect usually occurs without any feeling of drowsiness when taking Picamilon powder at the recommended dosage levels. For this reason, it may be a better nootropic to use for anxiety relief in comparison to Phenibut which is known to induce fatigue.
Picamilon Usage:
The recommended daily dosage range of Picamilon is between 50 and 300 mg. While it can be effective on its own, most people prefer to use it in a nootropic stack to produce more powerful results.
It works particularly well with Aniracetam which is another anxiolytic nootropic known to boost serotonin and dopamine levels. You may want to try a stack consisting of Picamilon, Aniracetam and CDP Choline or Alpha GPC for the best results.
Unlike Phenibut, Picamilon is not likely to cause symptoms of tolerance or withdrawal. It is safe to use every day and has neuroprotective properties with little risk of side effects. The one thing to keep in mind is you should not take it right before bed as the Niacin may make it difficult for you to fall asleep.
You can purchase Picamilon online from a number of popular Nootropic supplement retailers.
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- Mirzoian RS, Gan'shina TS. [The new cerebrovascular preparation pikamilon]. Farmakol Toksikol. 1989
- Bugaeva LI, Spasov AA, VerovskiÄ VE, Iezhitsa IN. [Preclinical prognosis of pyracetam and picamilon safety based on acute toxicity data]. Eksp Klin Farmakol. 2003
- Karaev AL, Kovler MA, Avakumov VM, Kopelevich VM, Bulanova LN. [Antihypoxic properties of GABA-containing vitamin derivatives]. Farmakol Toksikol. 1989
- Silkina IV, Gan'shina TC, Seredin SB, Mirzoian RS. [Gabaergic mechanism of cerebrovascular and neuroprotective effects of afobazole and picamilon]. Eksp Klin Farmakol. 2005
- VoznesenskiÄ AG, Kovalev GV, Sazhin VA. [Comparative study of the effect of picamilone and piracetam on learning in rats in a radial maze]. Farmakol Toksikol. 1989
Article last updated on: March 13th, 2018 by Nootriment
1 Comment
Buenas tardes,
Quisiera saber si PICAMILON produce adicción
Asimismo, quisiera saber si es compatible con 5htp triptófano.
Muchas gracias