Piracetam is perhaps the most well-known, used, and tolerated of all Notropics on the market today.
The effects are noticeable and may be beneficial in a number of areas that range from focus and cognition to even enhanced energy levels.
One of the few problems or issues with Piracetam, however, is that it is not nearly as potent as many of the newer Nootropics today.
This is somewhat to be expected as it was first developed in the 1960’s as the first nootropics from which all subsequent more powerful Racetams have been derived. Given this, smart Piracetam users often decide that developing a nootropic stack is worth their time.
Which other Nootropics would make good partners in a Piracetam stack? Here are some of the most popular Piracetam stacks that users have tried.



- Promotes neuron health & synaptic plasticity
- Supports memory recall & learning
- Boosts focus, visual perception & attention
Understanding Piracetam and Your Objectives
Related Topics
- What is Piracetam?
- What is Nootropil?
- User Reviews
- What to Expect
- Effects and Benefits
- How to Take
- Suggested Dosages
- Side Effects
- Dangers & Safety
- Top Piracetam Uses
- Effects on Memory
- Piracetam for ADHD
- Where to Buy
- Bulk Piracetam Powder
- Is Piracetam Legal?
- Piracetam vs. Aniracetam vs. Oxiracetam vs. Pramiracetam
- Comparison to Noopept
- Top Piracetam Stacks
- Stacking with Choline
The first step in this process is to really understand how Piracetam works, what benefits you are currently seeing using Piracetam alone, and what additional goals you are looking to accomplish.
For example, while Piracetam may increase your mental energy and even possibly physical energy, in certain circumstances the effects are mostly mental and related to synaptic plasticity.
Piracetam is believed to work by increasing the activity of the neurotransmitter Acetylcholine, and possibly additional neurotransmitters as well. Additionally, it is believed to increase blood flow to the brain.
Memory processes and learning capabilities tend to expand. Additionally, it helps to improve communication between both hemispheres of the brain.
If you are seeing these effects, then the next step is to determine what else you are after. For example, possibly you are looking for a nootropic stack to enhance your creativity.
Maybe you want to add a nootropic for stress or to promote anti-aging and longevity. Or maybe you are simply looking to improve the effects and benefits you are already seeing from Piracetam.
Whatever the objective, it is important to consider your options for stacking Piracetam wisely.

- Promotes neuron health & synaptic plasticity
- Supports memory recall & learning
- Boosts focus, visual perception & attention
Alpha GPC—Piracetam Stack
The most basic and functional nootropic stack option is to add a high-quality choline supplement to Piracetam. There are several options for this including Alpha GPC and CDP Choline (Citicoline).
The reason why this is so important is the fact that when Piracetam activates the Acetylcholine receptor sites, the demand for this powerful neurotransmitter within the brain can increase. If the stores of Acetylcholine become depleted, then the receptors can experience “burn-out” and possibly cause headaches. Of the few reported side effects associated with Piracetam use, headaches are the number one side effect reported by users.
Since choline acts as a precursor to Acetylcholine, it is thought that providing the raw materials to produce more Acetylcholine may help avoid depletion of this neurotransmitter. A Piracetam Citicoline stack may be helpful in alleviating any headaches that you might be experiencing when taking only Piracetam, as well as working together to provide stronger effects then seen with either compound taken alone.
PAO Stack (Piracetam, Aniracetam and Oxiracetam)
Some people choose to use Piracetam together with Aniracetam and Oxiracetam to get the full range of benefits seen with the Racetam type of nootropics. Not only is this a powerful nootropic stack but it is also quite cost effective.
Aniracetam has effects which are fairly similar to Piracetam but it is considered faster acting. This combination speeds up the effectiveness of your nootropics while also enhancing noticeable benefits in focus and energy levels.
Oxiracetam works as a solid cognitive processing power enhancer. This stack will give you great cognitive benefits as well as improve your mood.
There are also a number of users that report feeling much more creative from this stack, with a noticeable difference in sensory perception as well as increased communication between the two hemispheres of your brain.
Of course, you could modify this stack by only using a Piracetam Aniracetam Stack or a Piracetam Oxiracetam Stack. As mentioned previously, it is also a good idea to add a choline source to this stack or any other stack which makes use of one of these Racetam compound.

- Focus longer, clear brain fog & feel more motivated
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- Contains 12 safe and natural nootropic ingredients
Pramiracetam And Piracetam
One of the most potent of the Racetam family, Pramiracetam has also been known to be stacked together with Piracetam. When taking these together it is best to do so with food since the Pramiracetam is fat soluble.
This stack will likely improve most of the benefits already received from the Piracetam. Interestingly, some users report that the stack helps to increase their drive and motivation, helping them to get much more work completed in shorter times.
Huperzine A – Piracetam Stack
The combination of Piracetam and Huperzine A is an interesting stack to consider for fans of natural nootropics. Huperzine A is compound that is derived from the Chinese club moss plant (Huperzia serrata). Huperzine is reported to potentiate Piracetam, making them more effective together than separately.
While Piracetam actually increases the levels of Acetylcholine in the brain, Huperzine is believed to inhibit the breakdown of this neurotransmitter. In essence, this combination is thought to not only improve the levels of Acetylcholine, but also increase the amount of time that the benefits are noticed.
As noted previously, this stack could also be improved with the addition of a quality choline source.
Conclusion
Piracetam is a very versatile nootropic and is legal in most countries in the world. It can be stacked or combined with almost any Nootropic agent. The most popular Piracetam Stacks tend to involve other Racetams, Choline, and natural nootropics like Huperzine A, but there is really no limit to the possible combinations.
The main thing to remember is to design your own stack based on the goals you are trying to accomplish and then benchmark your results with different combinations. This will allow you to create the perfect Piracetam stack to increase your intellect and fuel up your brain.
It is important to note that while many research studies have been conducted over the years and while Piracetam has been classified for years as a drug in many other countries around the world, in the US the FDA has not approved Piracetam as a drug to prevent or treat any conditions.
Piracetam also does not meet the qualifications to be classified as a dietary supplement, and cannot be labeled or sold as such. In the US, Piracetam is an unregulated, unscheduled compound, that is now considered an investigational new drug (IND).
However, it is legal to buy, own, and use Piracetam for personal use. Selling Piracetam within the US can be difficult due to FDA laws surrounding the sales and labeling of unregulated compounds, so there are not many US based suppliers anymore. Some American nootropic users will instead import from countries where the sale of Piracetam is legal.
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Article last updated on: March 13th, 2018 by Nootriment