Pregnenolone Benefits, Uses, Dosages and Side Effects

Pregnenolone is a steroidal hormone with several powerful nootropic benefits. It is used as a focus booster, mood enhancer and energy pill.

Recent studies have found it effective for improving memory, comprehension, and information processing and critical analysis.

According to Dr. Flood of the Geriatric Research Education and Clinical Center, “Pregnenolone is the most potent memory enhancer yet reported”.

Pregnenolone is also one of the most important hormones within the body, involved in the synthesis of many different types of chemicals and other hormones like androgens, estrogens, glucocorticoids, and more.

This supplement is considered to be a pro-hormone, which essentially means that it leads to the production, development, or synthesis of a number of other chemicals and hormones.

Pregnenolone is synthesized from cholesterol. This occurs primarily in the adrenal glands, but also within the liver, skin, brain, testicles, ovaries, and retinas (eye). As a steroid, this supplement acts as a precursor to DHEA, progesterone, testosterone, estrogen, and cortisol.

Even though this supplement has some very powerful metabolites, it is also considered to be without significant side effects and very limited anabolic, estrogenic, or androgenic activity.

Pregnenolone

Hormone Supplement

Longevity

Energy

Memory

How It Works:

• Helps maintain healthy hormone balance
• Supports memory & brain function
• Boosts energy, metabolism & focus

Dosage:

Between 5 - 50 mg per day

Safety:

Insufficient Research

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Pregnenolone Effects:

Pregnenolone is a natural hormone produced within the body, however many different factors can interfere with proper production of this compound.

Natural Pregnenolone production declines as we age. For these reasons, many individuals may benefit from boosting levels of this compound using dietary supplement.

When the supplement is taken orally, it is able to quickly pass through the blood-brain barrier and enter into the central nervous system. There are actually quite a number of different chemical and biological processes by which Pregnenolone works.

It is considered to be the ‘mother’ hormone of the body since it is the foundational precursor to DHEA, progesterone, testosterone, the estrogens, and even cortisol. It also helps to balance out a number of other hormone levels and works equally well for men and women.

It is also thought to work by modulating the transmission of messages from neuron to neuron. Specifically, Pregnenolone positively modulates NMDA receptors which are involved in many cognitive functions. These receptors normally respond to the neurotransmitter Glutamate and regulate the formation of new synapses on our neurons.

This process is used by the brain to encode new memories through something called Long Term Potentiation. As such, using a supplement like Pregnenolone may improve memory formation and lead to better information retention while learning.

Pregnenolone Benefits:

There are a number of benefits which have been attributed to this supplement. It may be able to slow down the effects of premature aging.

For example, clinical studies have shown Pregnenolone to relieve symptoms of rheumatoid arthritis and osteoarthritis.

Another effect is to reduce levels of cortisol, especially when they have previously risen to an excessive concentration. It also helps to boost natural immunity, dramatically relieve fatigue, and restore energy levels.

Pregnenolone is also effective at helping to restore and balance out one’s mood. Not only does it appear to promote a positive mental outlook, but it also alleviates a number of mood disorders, relieves symptoms of clinical depression, and even heals some of the pain associated with fibromyalgia.

The supplement alleviates chronic insomnia and other sleep disorders and helps with many symptoms of chronic degenerative diseases like diabetes, MS, and lupus. Pregnenolone is also reported to have benefits for those suffering from nervous conditions such as stress and anxiety.

It may additionally possess neuroprotective properties and speed up the repair of damaged neurons and nerves. Further benefits of Pregnenolone are those normally associated with Nootropic supplements.

A number of studies have shown that it can significantly enhance motivation, learning capacity and ability, and even long-term memory. Users during these studies also experienced heightened feelings of alertness and well-being. Those who seemed to be under the most stress benefited the most, at least as far as productivity was concerned.

Pregnenolone is also considered to be a powerful neurosteroid within the brain. This means that it is able to change, or influence the transmission of messages and brain signals from neuron to neuron. This process is also thought to be one of the things that influence our learning and memory functions. The supplement has also been shown to help repair the myelin sheaths around various nerve cells.

Pregnenolone Dosage:

The typical daily dosage range is anywhere between 5 and 20 mg per day. It may even be broken into two equal administrations, one in the morning and the other in the afternoon. Due to the sometimes stimulating effects of this supplement, you may not want to take it too late at night.

While Pregnenolone is one of the safest supplements around, it should still be approached cautiously; begin with the lowest effective dose, most likely 5 mg.

Pregnenolone Side Effects:

There are several known side effects associated with this supplement. The presence of side effects is directly linked to dosages consumed and users should not take this supplement for long periods of time. There are also some possible drug interactions and contraindications.

For example, men who have prostate cancer should avoid this supplement, since a higher testosterone level may worsen the condition. The same holds true for women with breast or ovarian cancer (may be worsened by the increased estrogen levels). Consider seeking medical advice before adding something like this to your regimen.

Pregnenolone Review:

Pregnenolone is a powerful, yet very safe, supplement with significant nootropic properties. It has been shown to improve brain function related to memory, learning and reasoning. User reviews also say it is highly effective for improving your mood, boosting concentration and giving you extra stores of mental energy.

In addition to these benefits, using Pregnenolone supplements can improve your whole body health and even slow down signs of aging. While Pregnenolone is not the most well-known nootropic out there, this natural compound it is quickly gaining in popularity and positive reviews. Some individuals recommend taking Pregnenolone with DHEA for enhanced results.

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