Primaforce Cissus quadrangularis powder and tablet supplements are popular among bodybuilders to cut body fat, improve lean muscle mass, and reduce joint pain.
Cissus quadrangularis (CQ), also commonly called Bonesetter, is a member of the plant family Vitaceae.
Cissus is a succulent vine that is botanically related to grapes. It contains significant amounts of certain antioxidant phytonutrients (plant chemical), including resveratrol, the antioxidant found in red wines.
CQ has earned a reputation as an effective agent for healing bones and strengthening bone tissues. Clinical research supports the antioxidant, anti-inflammatory, antibacterial, antidiabetic, analgesic, sedative and vasodilative properties of this plant.
No standardized FDA guidelines have been determined concerning CQ supplementation, and the FDA has not approved Cissus as a drug to prevent or treat any conditios. However, Primaforce Cissus is viewed as safe with few known side effects for healthy adults.



- Promotes joint health & pain reduction
- Sedative & muscle relaxing properties
- Supports weight loss & workout recovery
Benefits of Primaforce Cissus Quadrangularis Supplementation
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Primaforce Cissus supplements are marketed primarily towards for joint and bone pains, reaching and maintaining healthy weight goals, minimizing post-workout recovery times, and enhancing generalized immune system health as an antioxidant.
This bodybuilding supplement was popularized in Tim Ferris’s book The 4 Hour Body to control blood sugar levels, inhibit insulin secretion, and promote weight loss.
Primaforce CQ capsules contain a standardized extract formulation containing 40% total Ketosterones and 20% 3-Ketosterone. The recommended dosage is 1000 mg per serving, taken twice daily 30 minutes prior to meals.
Primaforce Cissus for Fat Loss
Several research trials have demonstrated that Cissus quadrangularis is effective for promoting weight loss in obese individuals. This supplement is even more effective when paired with White Kidney Bean extract. Studies have also shown it can block the absorption of fats and carbohydrates when administered before a meal. It may be able to reduce post-prandial blood sugar spikes, which could result in improved insulin sensitivity.
Cissus quadrangularis has been shown in human trials to reduce several factors that are related to the development of heart disease. It has been found to reduce the risk factors associated with metabolic syndrome and to promote healthy weight levels.
In addition to lowering bad LDL cholesterol, total cholesterol and triglyceride counts, CQ has been found to elevate good HDL cholesterol levels. CQ acts to improve liver functioning and stimulate bile secretion, thereby supporting detoxification. Additionally, Cissus acts to balance lipopolysaccharides in the gut which may improve microflora balance and reduce inflammation in the gastrointestinal tract.
Primaforce Cissus for Post-Workout Recovery
During periods of weight training and other vigorous physical activity, the muscles are stretched, pumped with blood, and torn in places. This tearing of muscle tissue, and the repair that it necessitates causes increases in muscle size, strength and endurance.
After workouts, time must be allowed for healing muscles that have been recently targeted with training. DOMS (delayed onset muscle soreness) results as the healing and repair process ensues. It is desirable to minimize the time needed for healing so that athletes and bodybuilders can train faster.
In order for muscles to repair themselves after workouts, nutrition, hydration, hormones and proteins are needed. Muscles receive all of these resources via blood in the circulatory system. By increasing circulation, it may be possible to speed up the recovery process to a small degree.
Cissus Quadrangularis has been observed to increase blood flow throughout the body by acting as a vasodilator.
Vasodilation is the relaxing of the inner linings of the blood vessels, capillaries, and of the heart. When vasodilation occurs, these inner linings, called endothelium, relax. As they relax, they become more elastic and open wider. With increased diameter, they are able to carry more blood volume without increasing blood pressure.
Primaforce Cissus contains several agents that promote vasodilation. This is believed to accommodate enhanced post workout recovery times.
Primaforce Cissus Side Effects and Safety
Cissus quadrangularis has been used in African and Asian cultures as a medicinal agent for many centuries. It is viewed as a safe supplement for human usage. The AMA of the United States has determined Cissus to be “Possibly Safe” for supplementation purposes, except for the following groups:
- Patients with systemic diseases like MS (multiple sclerosis), Type II diabetes mellitus and Lupus
- Anyone taking antihypertensive medications as CQ may cause blood pressure to drop too low
- Women who are nursing babies or are pregnant
- Patients who are scheduled for any upcoming surgical procedures
Anyone considering using Primaforce Cissus supplements should first consult with their doctor. Your doctor can help you determine whether you are contraindicated for this substance and whether there may be any interactions with supplements or medications you are currently taking. Proper dosage is dependent on many factors including age, weight, and health status, and your doctor will also be able to help determine the best dosage for your needs.
Possible side effects of improper or excessive use include nausea, headaches, gas, bloating, and dizziness.
Primaforce Cissus Dosing
Primaforce Cissus supplements come in capsules and powders. The manufacturer recommended serving size is 1000mg, taken twice a day for either form. The supplement is typically administered 30 minutes before meals to maximize the lipid and carb-blocking properties of this herbal compound.
The optimal dosage will depend on several parameters including age, gender, current state of health, diet, physical activity levels and more. The full benefits of Primaforce Cissus quadrangularis are much more likely to manifest if supplementation is accompanied by healthy lifestyle habits and daily choices.
Article last updated on: May 5th, 2018 by Nootriment