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ProArgi-9+ is a dietary supplement that contains L-arginine, L-citrulline, D-Ribose, important vitamins and the antioxidants resveratrol and grape skin extract.
ProArgi-9+ is a drink mix manufactured by Synergy Worldwide designed to support heart heath.
The key ingredient is L-arginine – a semi-essential amino acid which is said to enhance cardiovascular function. L-Arginine is a precursor to nitric oxide (NO) in the body.
Increasing NO levels is associated with various health benefits, including improved sexual function, blood flow, energy, inflammation, anti-inflammation and promoting fat loss and muscle mass growth.
ProArgi-9+ is used by athletes, health-conscious individuals who want to improve their cardiovascular health and older individuals who want to reduce signs of aging.
How does this L-Arginine complex supplement work and what are the benefits and possible side effects?
Pre-Workout
Muscle Growth
Sexual Health- Boosts nitric oxide production for workouts
- Reduces fatigue & promotes muscle growth
- Supports immune function & sexual health
Top L-Arginine Products* ❯ProArgi-9+ Supplement Benefits
Related Topics
- L-Arginine
- L-Arginine Benefits
- Benefits for Men
- Benefits for Bodybuilding
- Effects on Blood Pressure
- Arginine Aspartate
- Arginine Alpha-Ketoglutarate
- Arginine Pyroglutamate
- Arginine Ornithine and Lysine
- Suggested Dosages
- Food Sources
- Comparison to L-Citrulline
- Best Supplement
- Topical Cream
- 500 mg Tablets
- Arginine Extreme
- Buy L-Arginine Powder
- Side Effects
ProArgi-9+ may help to reduce the risk factors that are known to cause heart disease.
Heart disease refers to a group of conditions that decrease the health and functionality of the heart muscle.
Cardiovascular disease is an umbrella term used to denote diseases of the blood vessels, arrhythmias, coronary artery disease, and congenital defects that affect cardiovascular efficacy.
The major blood vessels which supply the heart muscle with blood are called coronary arteries. Coronary artery disease is diagnosed when the coronary arteries become damaged or weakened.
The most prevalent cause of coronary artery disease is the accumulation of arterial plaque deposits along the linings of the blood vessels and the heart muscle. This has been linked to high LDL cholesterol levels as well as oxidation of blood lipids.
By inhibiting the accumulation of arterial plaque, ProArgi-9+ may help to significantly reduce several of the primary factors associated with developing coronary artery disease.
Arterial plaque is comprised by cholesterol, waste from cells, fatty substances like triglycerides, calcium and a clotting agent called fibrin. When plaque deposits increasingly constrict arterial flow over time, the heart has to work harder to get blood delivered throughout the circulatory system.
ProArgi-9+ is promoted as supplement that can reduce these risk factors and support a healthy heart. According to the manufacturer’s website, “ProArgi-9+, with its combined ingredients, combats the negative effects of premature cardiovascular aging.”
How Does ProArgi-9+ Work?
The primary mechanism of action of ProArgi-9+ is vasodilation. Vasodilation occurs when Nitric Oxide causes the inner linings of the heart and blood vessels to relax.
These blood vessels then dilate or expand, allowing them to carry more blood without increasing cardiac workload.
When nitric oxide levels are increased in the body, the result is increased vasodilation. Research shows that taking an L-Arginine or L-Citrulline supplement can raise nitric oxide synthesis and promote vasodilation.
ProArgi-9+ contains both of these ingredients as well as other supplements that support healthy blood flow.
ProArgi-9+ Benefits
By accommodating vasodilation of the vessels and heart, ProArgi-9+ helps to:
- Improve circulation
- Support a healthy heart
- Promote normal inflammatory responses
- Reduce oxidative damage in the body
- Help maintain healthy blood pressure
- Enhance energy metabolism
- Improve cholesterol levels
- Lower triglyceride counts;
- May support weight loss;
- May promote muscle mass gains;
- Fight signs of aging;
ProArgi-9+ supplementation is said to help flush arterial plaque deposits from the inner linings (endothelium) of the vessels and heart.
Over time, this reduces the accumulation of plaque; thereby reducing the probability of developing atherosclerosis, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, coronary artery disease, and subsequently cardiovascular disease.
Coronary artery disease takes years to develop to the point of irreversible damage to the heart muscle. In almost every case, positive lifestyle and dietary choices can reverse its development.
L-Arginine Research:
Research on patients with coronary artery disease shows that L-arginine expanded the minimum luminal diameters of stenotic segments.
Diametrical blood vessel increases of 0.16 mm induced a 24% increase in post-stenotic blood flow.
During coronary artery bypass graft surgeries, L-arginine has been used for the prevention of decreased blood flow in grafts. Also, it has been effective at preventing increases in both vascular resistance and arterial pressure.
In human research, L-arginine administration has been effective at:
- Preventing reduced aortic reflection times;
- Increasing monocytic adhesion;
- Improving stroke volume;
- Increasing cardiac output;
- Decreasing systemic vascular resistance;
- Reducing overall heart rate;
- Reducing platelet aggregation;
- Reducing LDL-C oxidizability;
- Preventing thickening of aortic intimal;
ProArgi-9+ for Erectile Dysfunction
Consumer reviews and clinical evidence support the use of L-arginine supplements, like ProArgi-9+ , for improving markers associated with erectile dysfunction (ED). One study involved 47 men with OAT (oligoasthenoteratozoospermia syndrome) and mild ED symptoms.
Combined supplementation with 690 mg of L-arginine and 60 mg of Pycnogenol (pine bark extract) was administered daily. Results were noted after 2 and 4 months; showing significant improvements in sperm concentration, erectile function, orgasmic function, sperm quality and sperm motility.
When supplementing solely with L-arginine, 5 grams daily for at least six weeks has been used effectively against ED symptoms as well. Further, internet reviews on L-arginine’s effectiveness for treating ED seem favorable.
ProArgi-9+ Side Effects
According to the manufacturer, ProArgi-9+ supplements have a well-demonstrated history of safe usage. The ingredients found in this supplement are well tolerated when used individually and no serious adverse effects have been reported.
Anyone considering using ProArgi-9+ supplements should first talk with their doctors. This is especially true for patients who are taking medications for cardiovascular disease, diabetes, hypertension, erectile dysfunction and/or cancer.
- Lacchini R1, Muniz JJ1, Nobre YT2, Cologna AJ2, Martins AC2, Tanus-Santos JE3. Relationship between Arginase 1 and Arginase 2 levels and genetic polymorphisms with erectile dysfunction. Nitric Oxide. 2015 Oct 29. pii: S1089-8603(15)30025-2. doi: 10.1016/j.niox.2015.10.003. [Epub ahead of print]
- Stanislavov R1, Nikolova V. Treatment of erectile dysfunction with pycnogenol and L-arginine. J Sex Marital Ther. 2003 May-Jun;29(3):207-13.
- Kobori Y1, Suzuki K, Iwahata T, Shin T, Sadaoka Y, Sato R, Nishio K, Yagi H, Arai G, Soh S, Okada H, Strong JM,Rohdewald P. Improvement of seminal quality and sexual function of men with oligoasthenoteratozoospermia syndrome following supplementation with L-arginine and Pycnogenol®. Arch Ital Urol Androl. 2015 Sep 30;87(3):190-3. doi: 10.4081/aiua.2015.3.190.
- Lai X1, Kline JA2, Wang M3. Development, validation, and comparison of four methods to simultaneously quantify l-arginine, citrulline, and ornithine in human plasma using hydrophilic interaction liquid chromatography and electrospray tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 17;1005:47-55. doi: 10.1016/j.jchromb.2015.10.001. [Epub ahead of print]
- Kalman DS1, Feldman S1, Samson A1, Krieger DR1.A clinical evaluation to determine the safety, pharmacokinetics, and pharmacodynamics of an inositol-stabilized arginine silicate dietary supplement in healthy adult males. Clin Pharmacol. 2015 Oct 7;7:103-9. doi: 10.2147/CPAA.S84206. eCollection 2015.
- Bersani FS1, Wolkowitz OM2, Lindqvist D3, Yehuda R4, Flory J4, Bierer LM4, Makotine I4, Abu-Amara D5, Coy M6, Reus VI6, Epel ES7, Marmar C5, Mellon SH8. Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation. Brain Behav Immun. 2015 Oct 26. pii: S 0889-1591(15)30041-6. doi: 10.1016/j.bbi.2015.10.015. [Epub ahead of print]
- Toni M1, De Angelis F2, di Patti MC3, Cioni C4. Nitric Oxide Synthase in the Central Nervous System and Peripheral Organs of Stramonita haemastoma: Protein Distribution and Gene Expression in Response to Thermal Stress. Mar Drugs. 2015 Oct 30;13(11):6636-64. doi: 10.3390/md13116636.
- Duan X1, Li F1, Mou S1, Feng J1, Liu P1, Xu L2. Effects of dietary L-arginine on laying performance and antioxidant capacity of broiler breeder hens, eggs, and offspring during the late laying period. Poult Sci. 2015 Oct 13. pii: pev 283. [Epub ahead of print]
- Poortmans JR1, Gualano B, Carpentier A. Nitrate supplementation and human exercise performance: too much of a good thing? Curr Opin Clin Nutr Metab Care. 2015 Nov;18(6):599-604. doi: 10.1097/MCO.0000000000000222.
Article last updated on: April 5th, 2018 by Nootriment
11 Comments
I am on pro argine for over 4 months but for the last 3 weeks have developed a rash on my body which comes and goes and itches badly .
I welcome your comments on my continued use. I take a sachet in the morning and another before bed.( 2 daily)
After taking Proargi9+, “have developed a rash on my body which comes and goes and itches badly.”
Depending on individual, some might see healing crisis of such nature like rash, or itchiness, this is common, it’s the improvement in the blood circulation, hence improving oxygen supply, nutrients supply to all human organs, & body cells, hence repairing the whole body, this will take time, many type of healing crisis depending on individual, such as old wound inflammation, follow by recovery, watery stool, can sleep well after taking PA9+ at night, that is because some usually not enough oxygen in their system, hence they can’t adopt to sudden increase in blood circulation that brought more oxygen n nutrition to their body, feeling energize….
May I request how I can get it for my mother suffering from cancer.
Please I need urgent response
Hi Aderemi,
I’m so sorry to hear about your mother. ProArgi-9+ is available to buy on Amazon at this link. Please make sure to consult with your mother’s physician before having her take any dietary supplement to make sure it is appropriate with any other medications or supplements she is using.
In its Policies and Procedures document, Synergy WorldWide clearly states that “Team Members may not sell products on eBay, Amazon, or any other Internet auction/shopping site”.
Team members (authorized distributors) selling products on such platforms are not compliant with these policies and procedures. Team members participating in such activities are subject to disciplinary measures from Synergy.
May i know if the person who are taking hypertension medicine can he stop the medicine and take proArgi 9+?
Hi Bee Hong,
This supplement is not approved as a drug for the treatment of hypertension. To determine whether you can stop taking any prescribed medicines, it is important to consult with a doctor who knows your health history.
Synergy Worldwide PROHIBES ProArgi-9+ distributors via amazon website strom. The top is clearly described in the Rules and Procedures. So why are you advertising PA9+ on amazon on your website?
This product can be use or suitable for pregnancy women?
no
Buenas tardes
Donde podria conseguir este producto en Argentina?
Gracias