Pterostilbene powder may be the latest great advance in mankind’s ultimate quest – the search for ways to extend life span and augment brain power.
This natural, plant-derived compound has been shown to significantly impact cell health by cutting inflammation and fighting free radical damage. It improves vascular health and overall organ function, as well as delivering important cognitive benefits.
Indeed, taking a daily supplement of powder Pterostilbene can extend the longevity and healthy function of brain tissue and neural structures.
Read on to find out how Pterostilbene can fight all of the major causes of age-related decline.



- 4x more bioavailable than Resveratrol
- Powerful anti-oxidant for longevity support
- Reduces cortisol for sleep, stress & weight loss
A Plant-Derived Super Nutrient
Related Topics
Pterostilbene is a phytoalexin compound produced naturally in plant life as a means to fight infection.
It is structurally very similar to Resveratrol, a food sourced compound which is widely taken as a supplement to improve cardiovascular health, renew and protect cell integrity, and fight the symptoms of aging.
Pterostilbene has many of the same benefits, with the added advantage of being highly bioavailable, meaning it can be easily absorbed by the body and isn’t degraded in the digestive process. It is potent, yet has a short half-life of under 100 minutes.
Pterostilbene is also available in some foods, such as blueberries and cranberries, but in very small quantities. To achieve the most desirable cognitive benefits of Pterostilbene, it’s best to consume it as a powder supplement.
Pterostilbene Powder Fights Brain Inflammation
One of Pterostilbene powder’s most potent benefits is its ability to reduce inflammation in the tissues of the brain.
Inflammation is the immune system’s normal response to injury, infection, or other disturbances to tissue. Leukocytes swell the area, allowing antigens to be expelled and immobilizing muscle fibers so they can heal.
Inflammation is a critical part of healing, however over time, signaling of enzymes which trigger inflammation becomes confused and imprecise, resulting in chronic inflammation, the cause of many debilitating diseases related to aging.
Pterostilbene disables sphingosine kinase and phospholipase D, the immediate triggers of inflammation. In the brain, chronic inflammation can hinder the normal growth of neural connections, called synapses.
Over time, memories become harder to access and new thought patterns become harder to form. We see these symptoms in most Alzheimer’s Disease patients – the increasing inability to perform normal cognitive functions.
Pterostilbene powder can assist in creating a thriving neural environment – at any age. There is no reason that aging has to bring on inevitable decay. Perhaps in the near future, advanced supplementation with compounds like Pterostilbene will help us extend the natural vitality of our minds well into our 80s and beyond.
Pterostilbene And Cell Health
Problems with cell integrity, either through molecular damage via oxygen (oxidation) or toxins, is the origin cause of many of the deadliest diseases we face as life progresses. Cancerous cells mutate and metastasize, poisoning neighboring cells until critical damage is sustained.
Heart disease, lung disease, and vascular breakdown all have their roots in cellular damage. Pterostilbene fights cell damage by destroying one its main causes, free radicals. These are oxygen-damaged molecules which threaten cell wall integrity and can cause the slow weakening of cells.
One of the more obvious signs of free radical damage comes in the form of wrinkles, as over time skin cells have been repeatedly weakened by free radicals until it sags. Pterostilbene powder can be a viable first defense against this kind of damage.
Pterostilbene also protects cells at the genetic level. The compound is able to influence gene expression – the directions from genes which give structure to the molecules which form every part of our bodies.
Pterostilbene can prevent genes from firing which will result in cell death, and it can also prevent the genetic expression of cancer cells, effectively stopping them from propagating. The two factors could play a huge role in preventing many causes of age-related decline.
Does Pterostilbene Powder Have Any Immediate Effects?
While many of Pterostilbene’s effects are considered long term, it does also produce some immediate, noticeable cognitive effects.
By preventing the loss of Dopamine, Pterostilbene can have an influence on the perception of mood and the lessening of nervous system disorder symptoms like anxiety or stress.
Pterostilbene can also facilitate cell signaling in the hippocampus via proteins. This results in a feeling of clear-headedness and mental flexibility.
These feelings become far more pronounced when Pterostilbene is stacked with other nootropic supplements, such as the combo product Alpha Brain.
Bulk Pterostilbene vs Alpha Brain Supplements
While Pterostilbene is available for sale as a stand alone supplement, many users refrain from adding to their daily regimen because the cost of bulk Pterostilbene powder seems prohibitive in relation to perceived benefits.
For the recommended daily dosage of about 300 mg, prices for Pterostilbene remain close to a dollar per dose, even in bulk amounts. That doesn’t sound like a lot, unless you consider that Pterostilbene should be taken daily for many, many years in order to truly reap its long term benefits.
With many other nootropic supplements, comparably priced daily doses will deliver powerful, immediate cognitive benefits. The best bet for exploring Pterostilbene supplementation is to take it in pre-measured combinations with other nootropics, such as Alpha Brain.
For significantly less per dose costs, you’ll get the same basis for long term Pterostilbene benefits, while enjoying the immediately apparent cognitive effects that the other ingredients, like L-Theanine, provide.
- Hou Y, Xie G, Miao F, Ding L, Mou Y, Wang L, Su G, Chen G, Yang J, Wu C. Pterostilbene attenuates lipopolysaccharide-induced learning and memory impairment possibly via inhibiting microglia activation and protecting neuronal injury in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2014
- Sato D, Shimizu N, Shimizu Y, Akagi M, Eshita Y, Ozaki S, Nakajima N, Ishihara K, Masuoka N, Hamada H, Shimoda K, Kubota N. Synthesis of glycosides of resveratrol, pterostilbene, and piceatannol, and their anti-oxidant, anti-allergic, and neuroprotective activities. Biosci Biotechnol Biochem. 2014
- McCormack D, McDonald D, McFadden D. Pterostilbene ameliorates tumor necrosis factor alpha-induced pancreatitis in vitro. J Surg Res. 2012
- Wang W, Ding XQ, Gu TT, Song L, Li JM, Xue QC, Kong LD. Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377. Free Radic Biol Med. 2015
- Sirerol JA, Feddi F, Mena S, Rodriguez ML, Sirera P, Aupà M, Pérez S, Asensi M, Ortega A, Estrela JM. Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis. Free Radic Biol Med. 2015
- Huang XY, Zhang SZ, Wang WX. Enhanced antitumor efficacy with combined administration of astragalus and pterostilbene for melanoma. Asian Pac J Cancer Prev. 2014
Article last updated on: March 26th, 2018 by Nootriment
2 Comments
HELLO,
A COLLEAGUE SUGGESTED THAT WE RECOMMEND YOUR PTEROSTILBENE POWDER AS A WORTHWHILE ADDITION TO A HEALTHY DIET.
WOULD APPRECIATE COUPLE OF SMALL SAMPLES TO TRY BEFORE ORDERING.
DO YOU OFFER PROFESSIONAL PRICING?
ALSO ANY PRINTED INFO SUITABLE FOR DISTRIBUTION?
THANK YOU,
DR. KERMIT J. HALPERIN [email protected]
7744 WIND KEY DRIVE
BOCA RATON, FL. 33434
Hi Dr. Kermit,
Thanks for your message. We don’t sell Pterostilbene ourselves, but we do link to AbsorbHealth which sells this supplement. I would recommend that you reach out to them!