Reishi D is a dietary supplement that combines reishi mushroom (Ganoderma lucidum), Cordyceps sinensis and Propolis extract.
This supplement is said to support a healthy immune system and promote good health. Each of the ingredients in Reishi D is a natural plant extract that has a long history of traditional medicinal use.
It is typically sold in 30 capsule bottles, with an effective total dose of 450 mg active ingredients per capsule. The recommended dose is 1 – 2 capsules per day.
What are the benefits of combining these three herbal remedies together? In this Reishi D reviews, we will examine the effects of each of these supplements as well as potential side effects and recommend dosages.



- Traditional Chinese immune modulator
- Promotes healthy blood pressure & cholesterol
- Anti-oxidant used for anti-aging benefits
Reishi D Ingredients Review
Related Topics
Each capsule of Reishi D contains:
- Ganoderma Lucidum Spore – 200 mg
- Ganoderma Lucidum Extract (30:1) – 300 mg
- Cordyceps Sinensis – 200 mg
- Propolis – 200 mg
Reishi mushroom (Ganoderma Lucidum), known in China as Ling Zhi, is said to promote longevity of life and improve overall wellness. According to The Chinese Materia Medica, “Ling Zhi strengthens the heart, increase vitality, and mental activity, and preserves one’s youthful complexion.”
Cordyceps sinensis is another medicinal mushroom that is used for its anti-aging effects, to boost the immune system and to enhance athletic performance.
Propolis is a natural plant resin collected by bees to fortify their hives. It has also been used as a natural medicine to boost the immune system, improve wound healing and alleviate gastrointestinal conditions.
Cordyceps Sinensis Review
Cordyceps Sinensis is a fungus that has long been used in traditional Chinese medicine. It is considered to be a versatile natural remedy, used historically to strengthen the mind and body and increase resistance to fatigue.
This mushroom extract is used to support kidney and lung function, improve libido, increase resistance to pain and help to prevent hyperglycemia. It is used as a tonic to nourish the Yin.
Research has demonstrated a number of medicinal effects from taking Cordyceps supplements. It shows anti-oxidant and immune-boosting effects. It has also been shown to improve insulin sensitivity, exhibit adaptogenic effects and help to reduce inflammation in the body.
While there is some promising initial research into this medicinal mushroom, most of its contemporary uses are based on historical tradition and anecdotal evidence. More research is needed to validate many of the health claims associated with this ingredient.
Propolis Review
Reishi D also provides 200 mg of propolis extract per serving. Propolis is sometimes referred to as “bee glue”. It refers to the dark resin that bees collect from plant leaves to help construct their hives.
This natural medicine was used since ancient Greek and Egyptian times to promote wound healing and to prevent infection. It was believed to improve the body’s natural defense system and resistance to disease.
Propolis has a positive effect on the immune system and exhibits antibiotic mechanisms. It is also a natural source of minerals, vitamins B C, E, and provitamin A, amino acids and more than 30 different flavonoids.
In research studies, it has been shown to exert anti-inflammatory, anti-oxidant, immunomodulatory and anti-cancer effects. Many of these results are based on in vitro studies and need to be replicated in human clinical trials in order for the findings to be validated.
Reishi Extract Review
The primary ingredient in Reishi D is Ganoderma Lucidum extract. Reishi mushrooms are used to promote health, immunity, resistance to infection and disease, and they are currently being researched for their anti-cancer effects.
Some of the reported effects of reishi extract include:
- Improving symptoms of CFS (chronic fatigue syndrome);
- Treating insomnia and other sleep pattern disorders;
- Exhibiting antiviral, antibacterial, antiprotozoal and antimicrobial effects;
- Supporting neurological function;
- Naturally reducing blood pressure and increasing blood volume displacement;
Reishi D and Cancer
The natural plant-based constituents in Reishi D supplements show clinical promise as anticancer and chemopreventive agents.
Beta-glucan polysaccharides, ganodermic acids, and flavonoids in reishi act to impede the onset and progression of tumors of various cancer cell lines.
Tumor cell walls become more rigid, making it more difficult for cancers to spread to neighboring cells. MAPK (mitogen activated protein kinase) signaling is enhanced. VEGF (vascular endothelial growth factor) production is suppressed. Blood and nutrients are cut off from tumor cells.
In one study, quality of life and survival ratings were increased for cancer patients when receiving Ganoderma lucidum extract supplements.
While these preliminary results are noteworthy, more research is needed to determine the efficacy of reishi mushroom for cancer treatment.
Reishi Extract and Heart Disease
All three ingredients in Reishi D are believed to improve risk factors related to heart disease. In research trials, reishi has been shown to reduce bad (LDL) cholesterol, raise good (HDL) cholesterol and lower total cholesterol.
It has also been found to decrease triglycerides, improve oxygen use, decrease heart rate, lower systolic blood pressure and induce endothelial relaxation (vasodilation).
These are all factors that may lower the risks for developing atherosclerosis, coronary artery disease, heart disease, stroke and other cardiovascular disorders.
Reishi D Antidiabetic Properties
Type 2 diabetes mellitus is a complex metabolic syndrome that is marked by high blood-glucose levels. This can result from either insensitivity to insulin or insufficient insulin secretion from the pancreas.
Nutrition, exercise and other lifestyle factors can be effective for controlling the symptoms of Type 2 diabetes.
Reishi mushroom extract has been researched for its effects on Diabetes, with preliminary clinical research showing that it may reduce hemoglobin A1C levels. This is a marker for diabetes and for elevated long-term blood glucose levels.
Managing blood glucose levels may play an important role in overall health and in the purported anti-aging benefits of this supplement.
Conclusions
Reishi D is a blend of three natural medicinal substances: Ganoderma lucidum mushrooms, Cordyceps sinensis mushrooms and propolis extract.
These three herbal remedies are said to boost immune function, improve energy levels and help to protect the body against stress, disease and infection.
Research has demonstrated that reishi, cordyceps sinensis and propolis do have a number of therapeutic effects. However, not all of the traditional uses for these supplements have been validated by clinical research trials.
Reishi D supplementation is not associated with any serious side effects. Some minor, temporary side effects may be experienced, such as stomach discomfort, headache, skin rash or dizziness.
The ingredients in Reishi D capsules may interact with certain drugs or dietary supplements. Check with your doctor to see if Reishi D is safe for you to take before using this supplement.
- Habtemariam S, Varghese GK The antidiabetic therapeutic potential of dietary polyphenols. Curr Pharm Biotechnol. 2014;15(4):391-400.
- Wang F, Zhou Z, Ren X, Wang Y, Yang R, Luo J, Strappe P. Effect of Ganoderma lucidum spores intervention on glucose and lipid metabolism gene expression profiles in type 2 diabetic rats. Lipids Health Dis. 2015 May 22;14:49. doi: 10.1186/s12944-015-0045-y.
- Batra P, Sharma AK, Khajuria R. Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum(higher Basidiomycetes): a bitter mushroom with amazing health benefits. Int J Med Mushrooms. 2013;15(2):127-43.
- Duffy AM, Bouchier-Hayes DJ, Harmey JH. Vascular Endothelial Growth Factor (VEGF) and Its Role in Non-Endothelial Cells: Autocrine Signalling by VEGF. In: Madame Curie Bioscience Database [Internet]. Austin (TX): Landes Bioscience; 2000.
- Liu, Dongbo et al. "The Genome of Ganoderma Lucidum Provide Insights into Triterpense Biosynthesis and Wood Degradation." Ed. John Parkinson. PLoS ONE 7.5 (2012): e36146. PMC. Web. 3 July 2015.
- Wu, Qing-Ping et al. "Ergosterol Peroxide Isolated from Ganoderma Lucidum Abolishes MicroRNA miR-378-Mediated Tumor Cells on Chemoresistance." Ed. Ganjam V. Kalpana. PLoS ONE 7.8 (2012): e44579. PMC. Web. 3 July 2015.
- Yu, Guo-Jun et al. "Deep Insight into the Ganoderma Lucidum by Comprehensive Analysis of Its Transcriptome." Ed. Alfredo Herrera-Estrella.PLoS ONE 7.8 (2012): e44031. PMC. Web. 3 July 2015.
- Xu Z1, Chen X, Zhong Z, Chen L, Wang Y. Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities. Am J Chin Med. 2011;39(1):15-27.
- Lin ZB1, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 2004 Nov;25(11):1387-95.
- Silva D. Ganoderma lucidum (Reishi) in cancer treatment. Integr Cancer Ther. 2003 Dec;2(4):358-64.
- Ren, Ang et al. "Profiling and Quantifying Differential Gene Transcription Provide Insights into Ganoderic Acid Biosynthesis in Ganoderma Lucidum in Response to Methyl Jasmonate." Ed. Sung-Hwan Yun. PLoS ONE 8.6 (2013): e65027. PMC. Web. 3 July 2015.
- Huang, Yen-Hua et al. "Generation and Analysis of the Expressed Sequence Tags from the Mycelium of Ganoderma Lucidum." Ed. Ahmed Moustafa. PLoS ONE 8.5 (2013): e61127. PMC. Web. 3 July 2015.
- Liang, Zengenni et al. "Chemical Characterization and Antitumor Activities of Polysaccharide Extracted from Ganoderma Lucidum." International Journal of Molecular Sciences 15.5 (2014): 9103–9116. PMC. Web. 3 July 2015.
Article last updated on: March 12th, 2018 by Nootriment