Resveratrol benefits are currently being studied for the treatment of acne, Alzheimer’s, cancer, diabetes, lung and heart disease and obesity.
Studies have found a link between Resveratrol and improving longevity, with significant anti-aging effects.
Resveratrol is a member of a group of plant compounds called polyphenols. These compounds are thought to have antioxidant properties, helping to protect your body from free radical damage.
An 8 ounce glass of red wine has about 640 mcg of this supplement, while a serving of peanuts provides about 73 mcg. It can also be found in berries, cranberries, mulberries and pomegranates as well as red grapes, a common source of the extract.
Because of the dangers associated with drinking alcohol, it is not recommended to try and obtain surplus amounts through this method. Most of the U.S. supplements contain extracts from the Japanese and Chinese knotweed plant Polygonum cuspidatum.



- Anti-oxidant used to fight signs of aging
- Improves mitochondrial health & energy metabolism
- Reduces inflammation & increases blood flow
Resveratrol Benefits
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A 2005 study on aging skin in The FASEB Journal found that resveratrol may protect against aging when applied directly to the skin and can help skin damage caused by ultraviolet light.
It has also been found to help with the severity of acne. It can be used safely on the skin in topical creams for up to 30 days.
In 2009 review of studies on red wine’s health effects, the researchers concluded that Resveratrol supplement may aide against inflammation and neurodegenerative diseases. Studies have also shown the supplement may protect nerve cells from oxidative damage and the accumulation of plaque that leads to Alzheimer’s disease.
In the treatment of heart disease, a 2010 report from Molecular Aspects of Medicine noted this supplement may help decrease LDL (“bad”) cholesterol, prevent atherosclerosis and keep blood pressure in check.
For Lung diseases such as COPD (chronic obstructive pulmonary disease), research suggests that taking resveratrol, vitamin C, zinc, and flavonoids slightly reduces coughing and mucus production.
Additional Health-Boosting Effects
For diabetes and obesity treatment, researchers believe that resveratrol activates the SIRT1 gene. This stimulates production of the hormone adiponectin, that has anti-obesity properties and helps fight insulin resistance which is the precursor of diabetes. This study was published in the Journal of Biological Chemistry in 2011.
Previously published test-tube and animal-based studies show that this supplement may help speed up metabolism and counteract the formation of fat cells. The benefits of Resveratrol for weight loss continue to be explored.
A cancer treatment study published in 2011 in the Annals of the New York Academy of Sciences suggests that resveratrol may have anti-cancer effects. In a 2008 study on cell cultures, it helped suppress breast cancer progression in its earliest stages.
A 2007 report published in Cancer Biology & Therapy found that this supplement appears to affect all stages of carcinogenesis, where cells turn into cancer cells. Published in the journal Carcinogenesis, another 2008 study suggests that it may help prevent prostate cancer.
Many users take Resveratrol supplements for this benefit as part of a daily long-term regimen to reduce the risk of developing cancer.
How much to take?
Most supplements dosages for Resveratrol range from 200 to 600 mg to obtain maximal benefits.
In research trials, a human equivalent dose of 500 mg per day has been determined as optimal.
Resveratrol is thought to be safe when eating foods containing the supplement or when taken in a supplement doses up to 500 mg daily for up to 3 months. There are limited side effects reported when using this supplement at this dosage.
1000 mg Resveratrol Extreme Juice brand capsules by Life Smart Labs Inc. are sold on Amazon.com. The cost for 180 tablets is $35.89, SRP is $79.99. The suggested dose is two capsules for 1000 mg per day.
Solar Ray brand of Resveratrol capsules sold at Baldwin’s has 75 mg Japanese Knotweed as well as grape skin extract, grape seed and red wine extract as a source of Resveratrol. The cost is £10.49 for 30 tablets.
Viridian Woman 40+ brand Multi With Resveratrol, Pomegranate & Green Coffee Bean is a vitamin and herbal combination for women over 40. It has 100 mg grape skin extract. The cost is 60 Capsules for £24.95 on Baldwin’s.
Pureclinica brand has the closest human equivalent dosage that was used in laboratory studies. It sells for £26.99 for 90, 1000 mg tablets.
Resveratrol Contraindications
Those allergic to grapes or wine or the other sources used for the supplement should avoid this product.
It could interact with medicines like blood thinners, blood pressure drugs, cancer treatments, MAOI antidepressants, antiviral and antifungal medicines, NSAID painkillers, and supplements like St. John’s wort, garlic, and Ginkgo Biloba.
It is thought to be safe during pregnancy and breast-feeding as long as it is not from drinking alcohol. It should be stopped at least 2 weeks before surgery. If taking medications that change in the liver, such as Mevacor, Nizoral, Sporanox, Allegra and Halcion avoid this supplement.
Resveratrol benefits have important applications for treating various conditions of the skin, heart and lungs as well as in the prevention of cancer, diabetes and obesity. It is viewed as one of the best anti-aging supplements and has been shown to increase life span in mice trials.
While some researchers suggest that red wine is an appropriate source of resveratrol for deriving health benefits, supplements are able to deliver higher dosages without the harmful effects of drinking alcohol in unhealthy amounts.
- Heebøll S, Thomsen KL, Pedersen SB, Vilstrup H, George J, Grønbæk H. Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease. World J Hepatol. 2014
- Lam YY, Peterson CM, Ravussin E. Resveratrol vs. calorie restriction: data from rodents to humans. Exp Gerontol. 2013
- Ramis MR, Esteban S, Miralles A, Tan DX, Reiter RJ. Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases. Mech Ageing Dev. 2015
- Vang O. What is new for resveratrol? Is a new set of recommendations necessary? Ann N Y Acad Sci. 2013
- Francioso A, Mastromarino P, Masci A, d'Erme M, Mosca L. Chemistry, stability and bioavailability of resveratrol. Med Chem. 2014
- Bitterman JL, Chung JH. Metabolic effects of resveratrol: addressing the controversies. Cell Mol Life Sci. 2015
- Santos JA, de Carvaho GS, Oliveira V, Raposo NR, da Silva AD. Resveratrol and analogues: a review of antioxidant activity and applications to human health. Recent Pat Food Nutr Agric. 2013
Article last updated on: May 10th, 2018 by Nootriment