Resveratrol Plus is a dietary supplement sold by Country Life Vitamins that is purported to support cardiovascular function and healthy aging.
This supplement contains 100 mg of trans-resveratrol from Polygonum cuspidatum root extract. It also contains Grape Seed Extract, Grape Skin Extract and Pine Bark Extract.
Resveratrol and the other ingredients found in this product are recognized as natural anti-oxidants. According to the manufacturers, “Resveratrol may provide antioxidant support as well as promote the activation of the SIRT1 gene, often referred to as the longevity gene.”
The Resveratrol Plus supplement is used to reduce signs of aging in the body, support heart health, promote energy levels and improve skin health. Resveratrol capsules are also taken to support weight loss, healthy testosterone levels, physical performance, cognitive function and to boost the immune system.



- Anti-oxidant used to fight signs of aging
- Improves mitochondrial health & energy metabolism
- Reduces inflammation & increases blood flow
Resveratrol Plus Review
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Resveratrol is a hydroxystilbene molecule that has been identified as occurring in a number of different plant species.
Its most famous source is in grapes and red wine. Grapes naturally manufacture this compound to prevent the growth of gray mold on immature grapes.
Resveratrol is considered to be a catechin molecule and is also found in blueberries and blackberries. The source of this molecule found in the Resveratrol Plus supplement is not from grapes, however.
Resveratrol Plus uses Polygonum cuspidatum extract, also known as Japanese Knotweed. Most dietary supplements that contain this molecule use the Japanese Knotweed plant as the source because it is more economical than red wine extract.
Resveratrol Plus Benefits
Resveratrol Plus is promoted as an excellent source of antioxidants. Antioxidants are molecules in the body that seek out and destroy free radicals, which can cause oxidative damage.
Free radicals are scavengers that damage healthy cells in the body by stealing electrons from nearby electrons. A free radical is an atom that has at least one unpaired electron. These molecules are created naturally through the normal metabolic functioning of the body.
Free radicals are highly reactive and try to stabilize themselves by scavenging electrons from other molecules in the body. Over time, this can contribute to damage to cells and may speed up signs of the aging process.
Resveratrol and the other ingredients in the Resveratrol Plus supplement function as antioxidants by inhibiting oxidative reactions. This can have wide-ranging benefits for general health and wellness.
Resveratrol Plus for Cardiovascular Health
Resveratrol supplements are also used to support cardiovascular health. This supplement has been shown to exhibit positive effects on blood vessels and may improve circulation.
Administering resveratrol was found in vitro to increase endothelial NO synthase (NOS) expression. This enzyme is involved in the synthesis of Nitric Oxide (NO), which causes blood vessels to dilate and can increase blood flow throughout the body.
In one research study, Resveratrol was found to inhibit the adhesion of platelets to blood vessel ways, thereby reducing the likelihood of arterial plaque or blockages from forming.
Resveratrol Plus capsules are also used to reduce risk factors for atherosclerosis, or hardening of the arteries. It may also improve high levels of low-density lipoprotein (LDL) cholesterol.
Resveratrol Plus Ingredients
Resveratrol Plus capsules from Country Life provide 100 mg of resveratrol per serving, in a complex with other antioxidant ingredients. The other compounds found in this supplement include:
- 50 mg of Grape Seed Extract (vitis vinifera)
- 25 mg of Grape Skin Extract (vitis vinifera)
- 25 mg of Pine Bark Extract (pinus spp.)
Grape Seed Extract is a source of polyphenols and flavonoids which can have benefits for cardiovascular function, blood pressure and reducing inflammation in the body.
Grape Skin Extract and Pine Bark Extract are both sources of proanthocyanidins, which exhibit anti-oxidant effects and may help to boost circulation and improve blood sugar metabolism.
Together, these ingredients are believed to enhance the heath of blood vessels, improve energy metabolism and enhance cardiovascular health and wellness.
Is Resveratrol Plus Safe?
Consumers are advised to consult with their doctor before purchasing any new supplement to determine whether this product is appropriate for you. Supplements can interact with medications or with pre-existing health conditions to cause side effects.
Resveratrol is rated as Likely Safe by the Natural Medicines Database and is generally well tolerated with few side effects. The dosage provided in Resveratrol Plus is lower than the recommended dose of up to 250 mg a day for three months.
There have been few side effects associated with using Resveratrol supplements, including nausea and dizziness.
It is not recommended for pregnant women or those who are breast-feeding. Red wine catechins consumed from foods are safe for most people, including women who are pregnant or breast-feeding. However, it should not be used as a supplement due to insufficient research into the effects on developing babies.
Resveratrol Plus exhibits anti-blood clotting properties and may reduce platelet activity. These cells are important for the blood clotting processes. If you are taking anti-platelet or anti-clotting medications it is advised not to use any form of resveratrol. This includes the medications aspirin, Plavix, ibuprofen, naproxen, heparin, or warfarin (Coumadin).
Do not use Resveratrol Plus for at least two weeks before or after a surgical procedure.
Individuals diagnosed with certain cancers or conditions that are hormone sensitive such as a uterine fibroids and endometriosis should not use Resveratrol Plus supplements. Resveratrol may behave like the hormone estrogen in the body, increasing risk of side effects.
Individuals taking any liver medications including cytochrome P450 3A4 (CYP3A4) substrates should not take resveratrol, as interactions may occur. This is true for other medications that are metabolized by the liver, including Allegra, Halcion, Sporanox or Mevacor.
Discuss the benefits and potential side effects of Resveratrol Plus with a healthcare professional before taking this supplement for any specific medical conditions.
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Article last updated on: March 25th, 2018 by Nootriment