How Rhodiola Rosea Extract Works on Serotonin and Cortisol Levels

Rhodiola rosea extract is made from the roots of the Arctic or Golden Root herb, a plant that has been used for thousands of years in traditional medicine practice.

Today, Rhodiola is classified as an adaptogen – a natural substance that produces non-specific physiological effects that help ward off the negative effects of stress.

In addition to its adaptogenic properties, Rhodiola extract is also used to increase energy, improve cognitive performance and fight off fatigue. It is also used for mild depression, anxiety, post-workout recovery and cardiac disorders.

The Rhodiola rosea herb is indigenous to cool, high-altitude regions in Russia (particularly Siberia), Europe and North America. It has been traditionally used in these regions to improve fertility, strength and treat disease: Rhodiola rosea extract was used by the Vikings to improve strength and endurance, given to newlyweds in Siberia to support fertility and prescribed to treat cancer and tuberculosis in Mongolia.

It has many common names, including Golden Root, Siberian Root, Kings Crown and Rose Root, among others.

Rhodiola Rosea

Adaptogen Supplement

Mood

Stimulant

Athletics

How It Works:

• Adaptogenic herb for reducing stress
• Boosts energy, focus & mood
• May reduce sleep problems & irritability

Dosage:

Between 200 - 1000 mg per day

Safety:

Rated Possibly Safe

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Rhodiola Rosea Extract

The majority of Rhodiola rosea supplements on the market are made from the root of the plant. Rhodiola rosea extract is a liquid concentrate produced by decocting the plant’s roots. Extracts are a common form of highly concentrated herbal supplements.

Rhodiola rosea extract is generally taken for its adaptogenic properties. Adaptogens possess three main characteristics: they have a non-specific impact on the body; are non-toxic; and promote homeostasis or balance in response to environmental, chemical, physiological or psychological stress.

Rhodiola’s mechanism of action has not been definitively established. This herb contains a number of phytochemicals (plant chemicals) unique to the Rhodiola genus, including rosin, rosarin, rosavin and salidroside. These phytochemicals are thought to play a role in the plant’s therapeutic effects.

When purchasing Rhodiola rosea extract capsules, look at the label ingredients: the supplement should contain no less than 3% rosavins and approximately 1% salidroside for greatest efficacy. Rosavin is one of the main components of the plant. It is a glycoside compound that is hypothesized to help reduce symptoms of depression.

Salidroside is thought to enhance mood by producing an antidepressant effect. It is also thought to support the nervous system, reduce stress and exhibit anti-aging properties. These effects may be related to the plant’s antioxidant properties, which help protect the body against free radical damage.

How does Rhodiola Rosea Extract affect the Body?

Preliminary research indicates that Rhodiola rosea extract works in the body by modulating an enzyme called monoamine oxidase. There are several subtypes of monoamine oxidase, all of which exhibit different functions: for example, one subtype is responsible for metabolizing serotonin and caffeine, while another subtype is responsible for metabolizing dopamine.

By inhibiting certain subtypes, Rhodiola may help increase the levels of some neurotransmitters. For instance, when monoamine oxidase is inhibited, the body increases the synthesis of serotonin.

Serotonin is known as the “happy hormone” and, when coupled with dopamine, often confers a sense of overall wellbeing. Serotonin and dopamine also have an impact on focus, attention, cognitive function and energy.

In addition to its impact on serotonin and dopamine, Rhodiola rosea extract has been observed to reduce the production of cortisol (the so-called “stress hormone”). Cortisol is produced during periods of physical or emotional stress.

Among its many physiological effects, cortisol interferes with the healthy function of the immune system. It can also affect insulin levels as well as fat, carbohydrate and protein metabolism. The impact of cortisol on metabolism is one of the reasons why weight gain, especially around the midsection, is associated with prolonged periods of stress.

Rhodiola Rosea Extract Dosage

It is best to establish a Rhodiola rosea extract dosage with your healthcare provider. It is often difficult to establish a general dose because extract dosages are often based on age, overall health and wellness levels, as well any pre-existing medical conditions.

It also depends on the potency of the extract, which often varies by brand and manufacturer. In addition, liquid formulas or tinctures often contain small amounts of alcohol, which will impact dosages.

For these reasons, when taking Rhodiola rosea extracts, look to the label instructions provided by the manufacturer to establish a safe dose. If you’re still not sure, talk to a pharmacist, herbal practitioner, physician, or other healthcare professional to establish a safe and effective dose.

Rhodiola rosea: Safety and Side Effects

When taken as recommended, Rhodiola rosea extract is generally well tolerated. The Natural Medicines Comprehensive Database rates Rhodiola rosea as possibly safe when taken appropriately.

It also notes that dosages of 100 – 600 mg of R. rosea are generally considered clinically effective. However, when taking Rhodiola rosea supplements, it is important to remember that dose will vary according to the extract’s concentration. Be sure to follow the label instructions.

Any extract or herbal supplement can interact with other dietary supplements as well as prescription and over-the-counter medications. Be sure to speak with your doctor before taking Rhodiola rosea extract to make sure the supplement is right for you.

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