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Sarcosine is a metabolite of an amino acid (N-Methylglycine) that is found in biological tissues. It may have Nootropic and testosterone boosting properties.
This supplement is an intermediate and byproduct in glycine synthesis processes and degradation. Sarcosine is metabolized into glycine by the enzyme Sarcosine Dehydrogenase.
This supplement is found almost everywhere you look. Foods such as egg yolks, turkey, ham, vegetables, and legumes all contain Sarcosine. Also, this supplement is sweet tasting and it is actually used in the creation of products like toothpaste.
It is formed from the dietary intake of Choline and the metabolism of methionine (another powerful amino acid). It is then rapidly degraded into glycine, which is an important constituent of protein and plays a role in a number of physiological processes as a prime metabolic source of components of living cells.
Mental Function
Mental Function
Brain Health- Promotes brain health & communication
- Supports memory, reasoning & cognition
- oosts focus, mental clarity & attention
Sarcosine Effects:
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This supplement has several different mechanisms of action stemming from the fact that it aids multiple metabolic processes within the human body.
One of the most interesting of these is its ability to raise testosterone levels naturally when combined with D-Aspartic Acid (DAA). This type of stack has also been added to a number of recent supplement products.
Sarcosine also acts as a type 1 glycine transporter inhibitor and agonist. This also means that supplementation will increase glycine concentrations in the brain and lead to NMDA receptor activation.
Many times, this action results in Nootropic effects and noticeable cognitive enhancement. To a degree, Sarcosine appears to work as a type of glycinergic re-uptake inhibitor.
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Sarcosine Benefits:
Sarcosine helps to increase natural testosterone production in the body. This happens through the stimulation of receptors located within the hypothalamus area of the brain along with the pituitary gland and the testes. This promotes increased production of gonadotropin releasing hormone (GRH), which in turn stimulates the pituitary to release more lutenizing hormone and follicle stimulating hormone.
Together, all of these hormones stimulate the testes, leading to more testosterone. Studies indicate that these effects are even more pronounced when Sarcosine is used in combination with DAA.
There is also mounting evidence to suggest that Sarcosine may be an effective supplement in treating conditions like Schizophrenia. One of the reasons for this is how glycine actually effects the NDMA receptors within the brain.
By increasing the amount of glycine available to help work, Sarcosine has been show to lead to some promising benefits like helping to increase the function of these receptors.
Sarcosine is also thought to improve cognition and mental processes. This is also likely related to the effects of the glycine actually binding to the Glutamate (and other) receptors within the brain. There is evidence suggesting that this is capable of helping to increase memory, expand learning capacity and even improve the speed of memory recall.
In short, this supplement appears to work similarly to a Nootropic. This effect is also thought to help healthy adults as well as Alzheimer’s patients and those undergoing treatment for degenerative cognitive issues.
Sarcosine Dosage:
Although a recommended dose has not been established, most research on the subject suggests using between 1,500 and 3,000 mg once or twice a day.
Splitting the daily dose into two different administrations also appears to be more effective, helping to ensure a consistent supply.
Most new users should start with smaller doses in the beginning. The general principle is to begin with the lowest effective dose and then only increase after becoming more familiar with how the effects present themselves.
Of course, it is also advisable to consult with a physician before adding this to your supplementation regimen.
Sarcosine Side Effects:
The research on whether Sarcosine produces side effects seems mixed at the moment. Most studies suggest that there are no significant side effects to speak of. However, you should also keep in mind the fact that supplements do have different effects on different people; it will not work exactly the same for everyone. This is especially true for supplements like Sarcosine that influence areas of the brain.
Having said that, you may experience some general side effects. They should typically be fairly mild like headache, fatigue, and possibly nausea, and gastrointestinal discomfort. Once again, the best strategy is to take things slow and carefully observe how this compound affects your body.
Sarcosine Review:
The most promising benefits for Sarcosine in a medical context seem to revolve around treatment for Schizophrenia and possibly other cognitive disorders. There is also the potential for this supplement to produce Nootropic-like effects on the brain. However, there many other Nootropics which are more powerful and have a proven history of positive user reviews.
Sarcosine may be effective for increasing memory performance when used in a stack and it is known to improve testosterone production. But if you are looking for a better experience with a memory boosting supplement, consider Noopept instead of Sarcosine supplements.
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Article last updated on: March 5th, 2018 by Nootriment
1 Comment
Wat een ontzettend slechte vertaling, rammelend “Nederlands”!Dit kan echt niet!
Doe er iets aan, want dit vergroot de leesbaarheid. Verschrikkelijk!