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Semax is a new heptapeptide nootropic that shares a similar history, potency and chemical make-up with Noopept powder.
Semax was developed in 1982 by a research team from the Institute of Molecular Genetics at the Russian Academy of Sciences in Moscow.
It was initially pursued as a treatment for stroke victims suffering bran damage but was subsequently determined to promote significant cognitive enhancement in healthy individuals as well.
This nootropic stimulates the Central Nervous System and increases memory, focus, mental and physical performance, and analytical skills. It is regarded as much safer than other stimulants and does not cause negative side effects like Adderall, Ritalin or Ephedrine. How does Semax work and what are some of the benefits of this drug?
Mental Function
Mental Function
Brain Health- Promotes brain health & communication
- Supports memory, reasoning & cognition
- oosts focus, mental clarity & attention
Semax Review
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Semax is a neuroactive peptide derived from corticotropin with the structure Pro8-Gly9-Pro10 ACTH(4-10).
It has been described as 1000 times stronger than Nootropil (Piracetam) which makes it similar in concentration to Noopept, Sunifiram and Unifiram.
Since 2011, it has been classified as a Vital and Essential drug in Russia. Clinical uses of Semax are common in Russia and the Ukraine where it is prescribed for its neuroprotective and neurorestorative characteristics.
It is particularly beneficial to ischemic stroke victims and individuals who have suffered other forms of head trauma but has also been used in the treatment of cognitive disorders, optic nerve disease and peptic ulcers.
Semax works by modulating receptors in the Limbic Reticular complex and for the neurotransmitters acetylcholine, dopamine, serotonin, adenosine, histamine and others. It also activates NMDA receptors for glutamate in the central and peripheral nervous system and enhances energy metabolism in your neurons.
Additionally, Semax increases synthesis of neurotrophins, proteins and biosubstrates to protect and repair neurons while also reducing inflammation. This drug exhibits highly neuroprotective properties and has been recorded to increase mRNA for Nerve Growth Factor by 500% and for Brain Derived Neurotropic Growth Factor by 800%.
The purported benefits of Semax are extensive, promising increased memory, learning, alertness, reasoning, perception, concentration, energy, immune system functioning and even better mood. Many of these benefits are derived from the fact that Semax has a psychostimulant effect, but it lacks the negative side effects that normally go hand-in-hand with CNS stimulants.
In some user experiences and reviews of Semax, it is described as lessening the perception of mental strain and allowing you to be more productive. Experience logs often state that this drug makes all of your cognitive tasks seem to flow easier, faster and with less effort.
- Focus longer, clear brain fog & feel more motivated
- Boost energy, alertnes & memory
- Contains 12 safe and natural nootropic ingredients
Other benefits related to learning and memory come from the fact that Semax boosts neuroplasticity and increases Glutamatergic and Cholinergic activity. Semax has been observed to improve the adaptive capacity of the brain to environmental sources of stress and to lessen symptoms of fatigue after long hours of exhaustive mental work.
It may be useful as a treatment for depression, anxiety and even sleep disorders by increases Dopamine and Serotonin levels as well. There is also the possibility of using Semax to cure or reduce signs of Alzheimer’s and other degenerative cognitive disorders or memory loss due to aging.
With such a wide range of mechanisms of action, Semax should be a fruitful topic of research in the coming years.
Semax Dosage
The effective dosage of Semax is said to be 1000 times smaller than Piracetam by weight. Semax is typically sold in a 0.1% or a 1% nasal spray solution in bottles of 3 ml which contain 60 doses each.
Some nootropic users are wary of taking Semax because it is administered as a nasal spray. While this does make it somewhat unique compared to other nootropic powders or pills that are ingested orally or dosed sublingually, you should not avoid Semax solely for this reason.
Ultimately this just means that Semax is more effective when absorbed into your system via the nasal mucous membrane as opposed to being passed through your digestive system.
The suggested dose of Semax for cognitive enhancement purposes is two to three drops of 0.1% solution in each nostril taken twice a day. This amounts to 50 mcg of active ingredient per spray which means if you were spraying twice in each nostril you would be getting 200 mcg of Semax per dosing.
Users may actually only need one dosage of Semax per day due to the very long half-life of the drug which can range from 12-24 hours. It is recommended that you cycle this drug for 14 days on at a time and then break from using it for 14 days before starting again.
The 1% Semax drop solution should be reserved for stroke victims or more serious medical purposes and should not be used for more than 14 days in a row.
Semax Side Effects
Despite its extremely high potency, Semax is considered safe with no serious side effects. There are no known interactions with other drugs, signs of addiction or symptoms of withdrawal from this nootropic drug.
It has an exceptionally low toxicity profile both in the liver and in the brain. However, it is important to remember that this is still a newer nootropic with less history of use in the world of brain enhancing compounds.
As such, there are fewer user reports to go on when determining the safety of this drug. This means that there are some inherent risks in taking such a novel substance even if early research indicates it is very safe.
Buy Semax
At present, there is limited distribution of Semax for nootropic purposes. While it is more available in Eastern European countries – particularly Russia – it has not been approved by the FDA and is not carried by many of the US nootropic vendors online. There are some websites where you can purchase it currently, but expect to pay a premium because it is so new.
Some people have reported buying Semax drops from websites and online pharmacies based out of Russia and the Ukraine with varying degrees of success. If you do order it online from another country, make sure they offer a refund policy in case the product is seized at the border by customs.
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Article last updated on: February 23rd, 2018 by Nootriment
27 Comments
The article mentioned 2-3 drops per nostril 1-2 times per day with a .1% solution. What would the dosage be with a 1% solution?
The 1% solution is generally reserved for use with doctor supervision since the minimum dosage would be 500 mcg per spray/dropperful. It may only be appropriate for patients with stroke or other severe neurological disorders. For anyone who this applies to, a doctor would be able to provide accurate dosing instructions depending on the needs of the patient.
If someone were to use the 1% solution as a nootropic, it would likely require dilution to prevent someone from using too much at once. Hope that information helps!
Can you it be shipped overseas? it says it needs a refrigeration or stored in cool place , is it possible to ship overseas?
Thankyou
Agus
Thanks for the information. I recently obtained some of the 1% solution and it should arrive any day. It seems I may want to look into diluting it then. Since it is administered nasally, that could prove challenging. I’m also wondering if maybe 1 drop every other day would work as well?
Hi, I realize that it’s been a while since anyone has commented here, but would the author happen to have any recommendations regarding suppliers of Semax?
two months is not a while. Three years is a while.
You’ve got my kinda sense of humor, guy
Legitimately hilarious.
Are you the supplier?
What if you stack Semax with some Racetams, or Noopept, or Alpha GCP? Or even with Modafinil? Is that a good idea?
Just asking..
If I have semax powder, can I swallow it?
How much I should swallow?
I can microdose the products.
yes. as much as you like; it won’t be effective.
Re: Semax
Where can I Buy it in switzerland??
Best,
wilde
I want to buy this .. Where can I buy semax in Pakistan or in Kyrgyzstan?
i know a suppler in China
I suffered from a lacunar stroke recently and as the result, the right side of my body feels thick and a a sense of icyness.
Will Semax helps in restoring the my thalamus nerve which has been the cause of this thickness and icyness sensation.
Strenghth wise and reflex wise, I am okay though. Memoray wise also still okay.
Please help me decide whether I should try SEMAX? And if so, for how long
Thank you
I doubt that tiny bit is going to do anything. I mix 30mg powder in a 30 mL bottle of Bacteriostatic water, then using a tiny needle (a sub-Q), I inject it just under the skin. Tutorial videos will show you how to mix powders and this water together for injection. It has provided an ability to be very focused for about 4-6 hours.
The powder is available online, in small bottles. Mixing is done by drawing a little water out of the water bottle, and injecting into the small power bottle, then shaking it. Then the mixture is drawn out and injected into the water bottle, and shaken. Then it is stored for when you want it. You draw out 1 mL, remove and air, then inject in any one of several areas known as areas for what is called “subcutaneous injection”. Painless and easy. But watch the videos and get a copy of the image showing what areas.
ps. It is stored in your refrigerator, preferably in a zip lock bag.
uh no
Simply because a substance can be dissolved in water does not make it suitable for injection
respect sir I want to buy semax nootropic spray I live in india please help me
ceretropic.com is a trustworthy and quality supplier. I have purchased semax spray from them.
Where is the third party tests hosted?
It has been 3 years.
Where can I buy semex now?
Ceretropic has nasal sprays :) Buy the N-Acetyl Semax Amidate though, as it is MUCH stronger
I want to make a Semax Order
Where can I buy SEMAX in Argentina?
it is so good,how can i get
Where can I buy Semax in Indonesia?