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Sun Pharma Modafinil is a popular alternative to the cognitive enhancement drug known as Provigil which is manufactured by Cephalon. Modafinil is an approved treatment by the FDA to treat narcolepsy, shift work sleep disorder, obstructive sleep apnea and excessive daytime sleepiness.
The drug is also prescribed off-label for ADHD and to improve energy, focus and mood. In the USA, UK, Canada and elsewhere it is necessary to have a prescription in order to purchase Provigil. However, Sun Pharma Modafinil can be purchased under the name Modalert without a prescription in certain countries where it is available over the counter.
Is this a trustworthy brand and how does it compare to the non-generic forms of Provigil tablets? Furthermore, how can you be sure that you are purchasing an authentic version of Sun Pharmaceuticals Modalert and not a counterfeit?
When purchasing drugs internationally (especially through online pharmacies), it can be very difficult to ascertain quality and purity from the manufacturers. This is why it is essential to read Sun Pharma Modafinil reviews posted online to ensure that individuals are ordering from a legitimate vendors.
Alertness
Mental Acuity
Focus- Stimulates wakefulness in the brain
- Promotes mental acuity & processing
- Enhances focus, motivation & energy
History and Uses of Modafinil
Related Topics
- What is Modafinil? (Provigil)
- How Does Provigil Work?
- Effects and Benefits
- User Reviews
- Typical Experiences
- Recommended Dosages
- How to Take
- Provigil Uses
- Use for ADHD
- Effects on Weight Loss
- Negative Side Effects
- Abuse Warnings & Dangers
- Comparison to Adrafinil
- Comparison to Armodafinil
- Comparison to Adderall
- Where to Buy
- Generic Modafinil Brands
- Is Modafinil Legal?
- How to Get Modafinil
- Review of Online Sources
Modafinil was first discovered in 1976 by Michel Jouvet, a neurophysiologist, for the French pharmaceutical company, Lafon Laboratories (which was subsequently bought by Cephalon Inc). The discovery of Modafinil actually occured because of research on the compound Adrafinil.
Adrafinil is one of a series of benzhydryl sulfinyl compounds that were developed in 1974. In research that was trying to determine Adrafinil’s mechanism of action, Modafinil was discovered. In the body, Adrafinil is broken down in the liver into the active Modafinil, and the inactive modafinilic acid. This makes Adrafinil a pro-drug of Modafinil.
Adrafinil and Modafinil are classified as eugeroics, or wakefulness-promoting agents. They have stimulant-like effects in the body, and promote wakefulness, alertness, and vigilance. Because of these known effects from animal trials, the first human clinical trials on Modafinil were using the compound as a treatment for narcolepsy.
Narcolepsy is a sleep disorder that affects the maintenance of wakefulness. People with this neurological disorder often experience excessive daytime sleepiness and typically have trouble staying awake during the day; they may also fall asleep randomly throughout the day. Multiple double-blind placebo-controlled research studies have been conducted using Modafinil for narcolepsy.
It has been seen many times that compared to placebo, Modafinil significantly improves wakefulness and decreases excessive daytime sleepiness. Improvements have been seen on various sleep rating tests, including the Maintenance of Wakefulness Test, the Multiple Sleep Latency Test, and the self-administered Epworth Sleepiness Scale that is given to patients to rate their own perception of sleepiness during the day.
Modafinil has been approved as a prescription drug to treat narcolepsy. Since its original testing and use for narcolepsy, Modafinil has been tested for improving wakefulness in other sleep disorders, namely obstructive sleep apnea/hypopnea syndrome and shift-work sleep disorder.
Obstructive sleep apnea/hypopnea is a medical condition that affects breathing during sleep. The muscles that keep the tongue and soft palate in place in the mouth can relax during sleep, and either partially block the airway causing shallow breathing (hypopnea), or completely block the airway, causing breathing to stop entirely (apnea).
People with this condition often wake multiple times a night and have overall poor sleep quality; consequently, they often experience excessive daytime sleepiness.
In multiple double-blind placebo-controlled studies, it has been seen that Modafinil is significantly better at reducing excessive daytime sleepiness in people with obstructive sleep apnea/hypopnea than a placebo. Modafinil is therefore often used as an adjunct treatment to treat this common symptom of this condition, in conjunction with a continuous positive airway pressure (CPAP) machine to manage the apnea/hypopnea itself during sleep.
Another sleep disorder that often involves excessive sleepiness is shift-work sleep disorder. This circadian rhythm disorder can arise in people who work the late/overnight shift. They are therefore awake and working during normal sleep hours at night, and trying to sleep during normal awake hours during the daytime. This shift in sleep/wake cycle can cause excessive sleepiness when awake, as well as potential insomnia when trying to sleep.
Studies have shown that compared to placebo, Modafinil is better able to improve wakefulness in patients with this disorder. One study gave patients a dose of either Modafinil or a placebo before they started a work shift at night. They were tested using the Psychomotor Vigilance Test.
Performances on Modafinil were significantly improved over placebo, with a lower frequency and duration of attention lapses recorded. The participants did say that they still experienced some residual sleepiness, causing the researchers to conclude that even better treatments are still needed to better manage this disorder.
Other research has been done on using Modafinil to improve the fatigue associated with various diseases. Studies on using Modafinil to reduce fatigue and improve wakefulness have been conducted involving patients with depression, multiple sclerosis, Parkinson’s disease, and chronic fatigue syndrome. As is to be expected given its wakefulness-promoting effects in sleep disorders, in all of the studies, Modafinil has been seen to reduce fatigue significantly compared to placebo.
Due to its stimulating effects, Modafinil has also been extensively studied for its use in managing attention-deficit disorder (ADD) and attention-deficit hyperactivity disorder (ADHD). Modafinil has been tested against a placebo alone, and in some cases tested against a conventional stimulant medication as well as a placebo.
In one randomized, double-blind, placebo-controlled, three-phase crossover study, Modafinil was tested against dextroamphetamine (Dexedrine), and both medications were tested against a placebo. Tests of improvement were administered during each of the two treatment phases and the control phase, and included the DSM-IV ADHD Behavior Checklist for Adults, the Controlled Oral Word Association Test (COWAT), Stroop Effect Test, and the Digit Span test (Wechsler Adult Intelligence Scale version).
Scores on the DSM-IV ADHD Checklist and the COWAT were seen to significantly improve with both active medications compared to placebo. The reseachers concluded that Modafinil should be considered a viable treatment option for ADHD.
One of the most common uses of Modafinil today is as a nootropic smart drug to improve cognition. Many people, from university students to high powered executives to Silicon Valley entrepreneurs use Modafinil to improve their memory, concentration, learning ability, and focus.
There have been some literature reviews done on the research studies done on Modafinil’s effects on cognition. The trend from all of these studies has been that Modafinil may increase memory, specifically working and episodic memory. It has also been seen to improve executive function, especially involving complex or difficult tests or tasks.
Modafinil is classified as a Schedule IV prescription drug by the FDA in the United States. It is similarly classified as a prescription drug in many other countries around the world. Its approved on-label uses are for narcolepsy, shift-work sleep disorder, and for obstructive sleep apnea/hypopnea; it is also sometimes prescribed off-label for ADHD, and for fatigue associated with various diseases. It is estimated at as much as 90% of all prescriptions are for off-label uses.
There are a few different brand or trade names of Modafinil, including the most common, Cephalon’s Provigil, Modapro, Modatec, and Sun Pharmaceutical’s Modalert.
- Increases energy, wakefulness and motivation
- Boosts mental performance and focus
- Supports memory and cognition
Sun Pharma Modafinil
The primary users of Modalert by Sun Pharmaceuticals are individuals who have prescriptions for this drug in the U.S., UK or Canada, but do not want to pay the high cost associated with Provigil.
A monthly supply of Provigil pills can cost as much as $600. Purchasing generic Modafinil brands like Modalert online is a fiscally sound alternative with pills costing as little as $1.50 per dosage.
There are also those who may seek out an international source of Sun Pharma Modafinil as a way to buy this venerated drug without a prescription. Individuals should take caution when purchasing modafinil via international online retailers.
In most countries around the world, using Modafinil legally requires obtaining a prescription from your doctor. If you decide to import it from other countries that do not require a prescription to buy it, you run the risk of legal prosecution.
Remember that Modafinil is a controlled substance in the USA which means your order may be detained or seized at the border unless it is accompanied by the appropriate prescription documentation.
Review of Benefits
In order for a drug to be marketed as a true generic, it must contain the same active ingredients as the original product at the same purity and dosage levels.
Modalert from Sun Pharmaceuticals lives up to these requirements and can be used as a cheaper substitute for Provigil 200 mg pills. The effects produced by this brand of Modafinil should be identical to those experienced with the Lafon brand.
According to user reviews, this bears out in most cases when purchasing Modalert. Most users report that it is an effective cognitive enhancer and promotes the characteristic wakefulness-enhancing effects that are apparent when using Provigil.
This drug is known as a eugeroic and was initially taken to help individuals with sleep disorders to stay awake during the day.
While the original applications may have been in the treatment of narcolepsy and sleep apnea, these effects also help to promote improvements in productivity, mental performance, and mood.
These recreational benefits of Modafinil have now surpassed the clinical uses as the predominant reasons for taking the drug.
Summary of User Experiences
There are numerous online sources to refer to when looking for reliable reviews on Sun Pharmaceuticals brand of Modafinil pills. Some of these sources include Reddit, Longecity, and other smart drug review communities.
We encourage you to read as many of these sources as possible to get an idea of which vendors are best and how the drug affects other users. In this section, we will provide a brief overview of some of the comments and common experiences.
The majority of users of Modalert state that it is an effective generic replacement for Provigil. Reports suggest that it produces a sense of natural, sustained energy and alertness.
Unlike other stimulant drugs such as Adderall or Ritalin, Modafinil does not cause a feeling of being “high” or over-caffeinated. You are not likely to experience jitters or restlessness like you would if you were to drink several cups of coffee or Red Bull.
Instead, the increased wakefulness and energy manifests as being more clear-headed and able to focus for long periods of time.
Sun Pharma Modafinil is an remedy for brain fog on those days when you find it difficult to concentrate or think clearly. It helps users develop greater attention and zone in on important tasks with razor-sharp focus.
There are also significant mood-related effects on motivation, anxiety and depression. Provigil has been explored as a treatment for depression due to its ability to lift mood, energy and drive.
The average Modalert user also reports that taking this drug can help to inspire feelings of confidence, ambition and excitement for life. Most people will feel better able to deal with anxiety (though in some cases users have reported an increase in anxious thoughts).
How Does Modalert Work?
There is ample evidence that Modalert and other brands of Modafinil produce positive effects on cognition and energy levels. However, what is less clear is the precise mechanism of action for this drug.
Research has established that this substance affects levels of histamine in the brain. This neurochemical is important in the regulation of sleep-wake cycles and the system in the brain that controls daytime alertness.
It is a well-known fact that if you take an anti-histamine drug (such as an allergy pill), drowsiness will result. In the same way, if you take a drug that increases histamine levels, it causes increased mental alertness so you feel less of a need to sleep.
It appears that Modafinil affects these pathways in such a way that the need for sleep is diminished and you have more energy during the day. It does this in a way that nighttime sleeping patterns are not usually negatively effected if it is taken early enough in the day.
Other pathways that have been identified as a target for Modafinil’s pharmacological activity include inhibition of the Dopamine transporter. Dopamine is the central neurotransmitter involved in movement and mood.
Specifically, it regulates the pleasure response and is involved in motivation, ability to focus, and executive function. This fits with the cognitive enhancement effects noted in Sun Pharma Modafinil reviews.
How to Use Sun Pharma Modafinil
Before taking Modafinil, Modalert or Provigil, it is important that you consult with a doctor to determine whether this drug is appropriate for you. They can then help you determine the right dosage and how regularly you should be using Modafinil pills.
The drug is usually administered at 200 mg per day, taken once a day early in the morning. It has a very long half-life which means you need to take it early to ensure it does not disrupt your normal sleep schedule.
When used for shift work sleep disorder, it should be taken one hour before the shift begins. The drug can be orally administered with or without food.
The information above pertains specifically to individuals using Modalert for sleep disorders, cognitive enhancement, or as an ADHD treatment. However, there are a number of other medicinal uses for the drug.
One growing use is as a weight loss aid. Modafinil has been noted to increase the rate of fat burning, even in people who are already maintaining a healthy weight.
It works both to suppress the appetite and to increase energy metabolism, resulting in steady weight loss. The most profound effects occur when taking 400mg per day.
Fake Modalert Sources
If you visit online nootropic communities regularly, you will occasionally see some negative reviews on Sun Pharma Modafinil. These negative experiences typically are characterized by users who felt almost no effects when using Modalert.
Certainly some percentage of users are not going to feel noticeable benefits when taking this drug due to individual sensitivities.
But it is also possible that some of these individuals inadvertently purchased counterfeit sources of Modafinil that were not manufactured by Sun Pharmaceuticals.
Counterfeits are an unfortunate reality in this industry since it can be difficult to determine the source of any given Modafinil pill.
Two companies may use largely similar synthetic routes to arrive at the same finished product, but different standards regarding purity can mean that the end results are not the same. Some manufacturers may include much less active ingredient in a tablet than what they advertise. Other manufacturers may substitute with less effective ingredients.
As such, it is imperative that you buy your Sun Pharma Modalert from well-reputed companies that provide third-part Certificates of Authenticity.
We are unable to recommend specific vendors on this site, but we suggest that you visit some of the prominent nootropics forums and communities online to hear about their experiences. Reading fellow user reviews can help you avoid fake Modafinil products from low-quality manufacturers.
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- Tsanov M, Lyons DG, Barlow S, González Reyes RE, O'Mara SM. The psychostimulant modafinil facilitates water maze performance and augments synaptic potentiation in dentate gyrus. Neuropharmacology. 2010
- Prasuna PL, Vijay Sagar KJ, Sudhakar TP, Rao GP. A Placebo Controlled Trial on Add-on Modafinil on the Anti-psychotic Treatment Emergent Hyperglycemia and Hyperlipidemia. Indian J Psychol Med. 2014
- Golicki D, Bala MM, Niewada M, Wierzbicka A. Modafinil for narcolepsy: systematic review and meta-analysis. Med Sci Monit. 2010
- Kim D. Practical use and risk of modafinil, a novel waking drug. Environ Health Toxicol. 2012
- Poot-Ake A, Mijangos-Moreno S, Manjarrez-Martin D, Jimenez-Moreno R, Aquino-Hernandez PR, Pacheco-Pantoja E, Arias-Carrion O, Sarro-Ramirez A, Arankowsky-Sandoval G, Murillo-Rodriguez E. Intrahypothalamic Administration of Modafinil Increases Expression of MAP-Kinase in Hypothalamus and Pons in Rats. CNS Neurol Disord Drug Targets. 2015
- Davies M, Wilton L, Shakir S. Safety profile of modafinil across a range of prescribing indications, including off-label use, in a primary care setting in England: results of a modified prescription-event monitoring study. Drug Saf. 2013
Article last updated on: April 29th, 2018 by Nootriment
1 Comment
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