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Vasopressin is today recognized as one of the strongest cognitive enhancement drugs available, though it is prescribed for very different reasons.
Vasopressin, sold under the name Diapid, also known as Arginine Vasopressin and antidiuretic hormone (ADH), is classified as a neurohypophysial hormone that is found in most mammals. It is amino acid peptide hormone secreted by the posterior portion of the pituitary gland.
Vasopressin is responsible for the regulation of electrolyte levels and is used as a treatment for individuals suffering from frequent urination. The two primary functions of this supplement are to retain water in the body and constrict blood vessels. To these ends, it has influence on the kidneys and is also thought to help play a key role in homeostasis through the regulation of water, glucose, and salts in the blood.
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Vasopressin for Memory
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While the intended use of this drug may be entirely unrelated to cognitive enhancement, studies have shown that smaller doses do lead to profound improvements in brain function.
Vasopressin has a significant impact on mental performance, especially as it relates to memory formation and information processing.
One study of middle aged men found that after administering 16 I.U. of a Diapid nasal spray, patients performed dramatically better on learning and reaction time tests. Other studies have found Vasopressin to possess anti-amnesiac effects.
Individuals suffering from amnesia due to physical trauma are reported to recover their memory within hours of taking Vasopressin.
On an anecdotal level, reviews state that this drug quickly eliminates brain fog and can give you almost eidetic powers of memory recall when studying for an exam or learning new information.
Vasopressin Effects:
It is not entirely known why Vasopressin works as a nootropic. However, Vasopressin is naturally produced in the brain and secreted by a small number of neurons. It is theorized that using a Diapid nasal spray increases levels of this peptide in the brain, resulting in improved memory formation and retrieval.
More is known about the mechanisms of action for Vasopressin on the kidneys and urination. By increasing water absorption in the collecting ducts of the kidney nephron, it helps to regulate the body’s water retention.
It also increases the water permeability of the kidney’s collecting duct and distal convoluted tubule. It works by controlling the tissue permeability (the ability of water and other substances to move through a membrane) of these areas of the kidneys.
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Another interesting method of activity for this supplement is related to the blood vessels. It increases the peripheral vascular resistance. This, in turn, also serves to increase arterial blood pressure.
Additionally, Vasopressin is thought to work by playing a key role in the process of homeostasis within the body. This is affected by the regulation of not only water but also glucose and salts within the blood. The supplement itself is derived from a preprohormone precursor that is synthesized in the hypothalamus and stored within the pituitary gland.
Vasopressin Benefits:
The evidence supporting Vasopressin’s nootropic effects is extensive.
Numerous users report they have achieved enhanced mental clarity, increased attention to detail, improved short-term memory, and also much improved memory imprinting.
It is also being considered in the treatment of memory deficits due to old age, dementia, drug toxicity, and amnesia. Further research continues into the role of this nootropic drug in social behaviors as well as response to environmental stress.
Another benefit of Vasopressin is that it helps to control water balance within the body. It serves to prevent too much water from being released as urine.
Although this may be something most of us take for granted it can come in handy for those with difficulty controlling their bladder or when we are in hot conditions without access to water. This anti-diuretic hormone instructs the body to conserve water and save itself from becoming severely dehydrated.
A related benefit to this might also be that Vasopressin can help treat some cases of diabetes insipidus, which is a condition in which too much water is excreted by the kidneys. This is actually a life-threatening condition, and one that Vasopressin has shown a remarkable ability to treat.
This supplement is also thought to increase blood pressure. It works more like a regulatory effect here, with the supplement only being released into the bloodstream when a decrease in blood pressure is detected. This leads to a restoration of healthy blood pressure levels. Vasopressin can also be used in situations where the heart stops beating (as an injection for quick effect).
Another benefit of Vasopressin is that it limits night time bladder voiding. The reason for this is effect is thought to be related to our normal circadian rhythm. To this end, children who urinate in bed beyond the age of 6 are thought to suffer from an alteration in their Vasopressin activity and it can also be prescribed for bed-wetting in older children as well.
Vasopressin Dosage:
The recommended dosage of this compound is determined by the purpose for its use. The actual dose is normally quoted in terms of units, with a single unit being equal to 0.05 ml.
Most experts seem to recommend that for more issues, adult patients should be taking between 5 and 10 units every few hours. As a cognitive enhancement drug, it has been recommended to use 16 IU per day, equivalent to one spray in each nostril approximately 4 times a day. If you are using Vasopressin for other medical conditions, it is important to find out from your doctor what the right amount to use it.
Vasporessin has a very short half-life so this is important to ensure a consistent supply with the body. If this is being used with children the dosage should be reduced accordingly.
Vasopressin Side Effects:
There are some side effects associated with Vasopressin usage, especially at higher doses. These include nasal itchiness, headaches, conjunctivitis, sore throat, nausea, abdominal pain, and the urgent need to defecate as a result of increased peristalsis.
This drug should not be taken by those who have cardiovascular problems or who need to avoid the possibility of increasing blood pressure. It is known to increase pain associated with angina and should be avoided by anyone with a history of heart problems. At low doses of 16 IU or less, it is not observed to increase blood pressure.
Vasopressin Review:
There are many in the nootropic community who will attest to this being one of the most potent memory boosters around. Vasopressin is observed to dramatically improve memory retention and mental clarity, giving your cognitive actions a higher degree of fluidity. Most individuals interested in using this nootropic take Desmopressin which is a high quality synthetic alternative to the expensive Vasopressin formulation.
While safety cautions need to be adhered to closely with this drug, at low doses it is observed to have minimal side effects. If you do decide to use this compound, it may be preferable to reserve it for occasional use instead of taking a Vasopressin dosage every day.
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Article last updated on: March 17th, 2018 by Nootriment