Nootropics are a class of cognitive enhancing supplements that are used to improve concentration and boost memory power. Nootropics are often used to increase attention spans, help individuals focus and as studying aids.
You will occasionally see Nootropics referred to as “smart drugs” as they are associated with increased intelligence, motivation, and mental energy.
However, unlike smart drugs which can often cause negative side effects with long-term use, nootropics must be safe, neuroprotective and pose a very low risk of side effects when used appropriate.
Many nootropics share similar mechanisms of action by enhancing increased communication between neurons, helping to balance neurotransmitter levels or by promoting brain cell health. They may help improve energy metabolism in your neurons, support neuroplasticity, or even stimulate the growth of new neurons and synapses.
What are Nootropics and how do they really work? Which are the best nootropics to use if you are a new user?
This article will provide a basic guide to nootropics and give you an overview of how to use these supplements to enhance your mental capabilities.
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What Are Nootropics?
Related Topics
- What are Nootropics?
- Nootropics List
- Types of Nootropics
- Effects & Benefits
- How Do Nootropics Work?
- Natural Nootropics
- Enhace Intelligence
- Boost Memory
- Improve Concentration
- Reduce Anxiety
- Treat Depression
- Nootropic Side Effects & Dangers
- How to Stack Nootropics
- Best Nootropic Stacks
- Strongest Nootropics
- Where to Buy Online
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- Are Nootropics Legal?
Nootropics are broadly any type of neuro enhancing drug or natural supplement with very low prevalence of side effects. The actual definition of what makes a supplement a nootropic is somewhat of a loose concept.
The original description comes from Belgian pharmacologists S. Giurgea and V. Skondia who invented the first Nootropic – a compound known as Piracetam – in 1963.
They established the classification of Nootropics to refer to cognitive boosting substances with extremely low toxicity that can be taken for long-term use.
This highlights the fact that Piracetam and other Nootropics are able to improve brain functions without any of the negative side effects associated with brain stimulants.
Piracetam (known also by the name Nootropil) is one of the best known Nootropics and makes up part of the Racetam family along with Aniracetam, Phenylpiracetam, Pramiracetam, Oxiracetam, Nefiracetam, Coluracetam and Nebracetam. These are all synthetic compounds that have been created in the lab, but there are also a number of effective herbal and natural nootropic supplements.
For example, fish oil, grape seed extract, bacopa monnieri, yerba mate and even licorice are all natural nootropics. (Click here to see a full Nootropics List of supplements that are available.) You will often find these supplements combined together in a Nootropic Stack to further enhance their effectiveness.
How Do Nootropics Work?
What exactly do Nootropics do? Like “smart drugs”, Nootropics will not instantaneously give you a higher IQ or a better intellect. But they may boost your brain functions by increasing the production and signalling of various neurotransmitters.
Your brain is essentially a network of billions of neurons connected by synapses. These neurons communicate and work together through chemicals known as neurotransmitters. When neurotransmitters are able to send signals more efficiently, you experience improved concentration, better memory, mood elevation, increased processing ability for mental work, and longer attention spans.
With continued supplementation of certain nootropics, you can improve the synaptic plasticity of neurons, causing long lasting improvement to the health and functioning of your brain.
Other nootropics show effects of vasodilation which means they increase the blood flow to your brain. This supplies your brain with more oxygen, nutrients, and glucose – the primary energy source used by the brain during long periods of focus.
The brain requires an immense amount of energy to perform its function, sustain consciousness and to pay attention to your external environment. Even though the brain is only 2% of your bodyweight, it constitutes 20% of your energy expenditure.
Performing mental exercises, learning new things, concentrating on your work and staying alert during the day all burn a lot of energy. By raising bloodflow and oxygenation, you can immediately experience greater capacity for memory and focus.
Supplements that can improve the energy supply to your brain cells (like Acetyl L-Carnitine, Caffeine, Creatine, Ginkgo Biloba, or Vinpocetine) can all enhance focus, mental energy and clarity. This type of nootropic is especially favored among students for studying as their effects are felt immediately.
Nootropics can also show signs of neuro-preservation and neuro-protection. These compounds directly affect the levels of brain chemicals associated with slowing down the aging process. Some nootropics could in an increase in the production of Nerve Growth Factor and Brain-Derived Neurotrophic Factor to stimulate the growth of neurons and neurites while slowing down the rate of damage as well.
Over time, this could potentially slow down signs of aging like loss of memory and even counter the development of disorders like Alzheimer’s disease.
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Nootropics List
Below is a list of some of the most popular and best nootropics that are available today. Each supplement with have its own unique mechanism of action that is distinct from other nootropics.
You can either select the supplement that best matches your needs or goals, or you can combine several nootropic compounds together in what is known as a stack. A stack simply involves any pairing of substances that enhance and complement each other when taken simultaneously.
Most of the pre-packaged brain boosters available will stack together several different herbal or synthetic nootropics like those listed below, but you can also buy the bulk raw powder and mix your own capsules to design a formula that is right for you.
Racetam: As mentioned previously, racetams are a class of nootropics including the widely used Piracetam, Aniracetam, Pramiracetam, and Oxiracetam.
They all share a similar chemical structure with a Pyrrolidone nucleus. Racetams work by dramatically increasing levels of neurotransmitters and other chemicals required for proper brain function like glutamate and acetylcholine.
They have been tested to improve cognitive function, prevent damage to brain cells from alcohol consumption and other factors, and to increase the communication between the two hemispheres of the brain.
Choline: Choline is frequently found in a nootropic stack with racetams like Piracetam and Aniracetam. Taking choline supplements will cause greater production of the acetylcholine neurotransmitter in the brain.
Since Racetams result in increased uptake and demand for acetylcholine, stacking choline with this nootropic will further enhance your results. Studies have shown that choline supplementation can improve performance on memory tests as well as social behavior. Choline also plays a key role in the production of phospholipids that are incorporated into brain cell membranes.
Pyritinol: Pyritinol has anti-oxidant effects for supporting the long-term health of the brain. But its primary benefit is aiding glucose uptake for periods of extended mental strain. If you are studying or working for a long period of time, your brain will start to diminish its glucose (sugar) stores which are the primary way that the brain derives its energy.
Psychological studies have shown that continuing to refuel your brain with glucose will improve concentration and cognitive ability during extended periods of mental work. Supplementing Pyritinol aids further in glucose uptake so that your mental energy levels are higher.
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Vinpocetine: Vinpocetine has been shown as one of the most effective nootropics for improving brain blood flow. After taking Vinpocetine, the blood vessels dilate and are able to circulate more blood to the brain.
This causes a number of immediately noticeable effects such as concentration boosting, better mental agility, and higher energy levels and motivation.
There are many more nootropics available out there and different ones can assist you in improving your brain in various different ways. For a full Nootropics List, keep reading this website and check out our many Nootropic reviews.
Which nootropic supplement you pick is largely a matter of personal preference. You might want to check out the pre-made nootropic products like Alpha Brain or you might prefer to design your own stack by purchasing ingredients like Piracetam powder.
The health and capabilities of your brain are one of the most important determining factors in a happy and successful life, so whatever you pick you can rest assured that you are making a smart investment.
3 Comments
I’m a noob to nootropics! I am on about day 10 for Alpha Brain and am starting to explore the possibilities of doing my own stack. Thank you for the link to buying in bulk!
A fascinating subject. The nootropics listed here are new to me. Where do they come from? I’ve only taken things like caffeine, creatine, b vitamins, and amino acids. Those all seem to help really well. I think the more natural the substance is, the better.
Great post, one that you can’t overlook that has been on the market the longest is Brain Fuel Plus. Thanks again.